Stage IVB endometrial cancer : clinical course and survival of patients with single and multiple metastases

Article Article scientifique Article Stage IVB endometrial cancer : clinical course and survival of patients with single and multiple metastases eng 2015 author Kraemer O. author Rapiti Aylward Elisabetta 134294 author Huber Daniela 788725 Département de Pédiatrie, Gynécologie et Obstétrique (PETRI) Daniela Emanuela Huber author Lopes Raimundo Elisabete 597648 author Usel Massimo 22657 author Bouchardy Magnin Christine 27853 author Petignat Patrick 586685 529-532 10.12892/ejgo2693.2015 26513877 0392-2936 https://www.ejgo.net/articles/10.12892/ejgo2693.2015 Objective: Metastatic endometrial cancer (EC) at initial presentation is a rare disease. The present aim was to evaluate prognostic factors and overall survival in patients diagnosed with metastatic EC. Study design: Using data from the Geneva Cancer Registry, the authors included all patients diagnosed with Stage IVB EC from 1980-2007. Estimates of survival were calculated using the Kaplan-Meier method and compared using the log-rank test. Results: A total of 38 patients were identified. The most frequent metastases were peritoneal or pleural carcinomatosis (66%, n=25) and hematogenous metastases (53%, n=20). Five-year survival rate was 5.7% (95% confidence interval: 0.0-13.3), and median survival was 7.6 months. Survival of patients with a single metastasis at the time of diagnosis was longer than for patients with multiple metastases (16 versus two months, respectively; p < 0.00 1). Conclusion: Metastatic EC is rare disease with very poor prognosis particularly for patients with multiple site metastases. Aged Aged, 80 and over Endometrial Neoplasms/mortality/pathology Female Humans Middle Aged Neoplasm Metastasis Neoplasm Staging Survival Rate Dewey 613 Dewey 618 58 Département de pédiatrie, gynécologie et obstétrique 223 215 Registre genevois des tumeurs 22A12 false 1311 Epidémiologie des tumeurs 1017 277 Groupe Bouchardy Magnin Christine (Registre genevois des tumeurs) 532 590 Prévention du cancer du col utérin 933 European journal of gynaecological oncology 36 5 19357726-07ae-4d6c-885f-2b5ebf5f459c Article (Published version) Public EJGO2693.pdf 176303 application/pdf OA OTHER c5af43d49133f1625c8d818ebc79bf4e00cf1bbea120435147d8a54856369b4e openAccess Faculté de médecine / Section de médecine clinique / Département de pédiatrie, gynécologie et obstétrique Faculté de médecine / Section de médecine clinique / Département de santé et médecine communautaires / Institut de santé globale / Registre genevois des tumeurs

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Stage IVB endometrial cancer : clinical course and survival of patients with single and multiple metastases	European journal of gynaecological oncology			2015	563	209

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Lopes Raimundo, Elisabete