Harmonizing neuropsychological assessment for mild neurocognitive disorders in Europe

Article Article scientifique Article Harmonizing neuropsychological assessment for mild neurocognitive disorders in Europe eng 2021-05-13 2022-01 author Boccardi Marina 0000-0001-6744-8246 850343 author Monsch Andreas U. author Ferrari Clarissa author Altomare Daniele 917820 author Berres Manfred author Bos Isabelle author Buchmann Andreas author Cerami Chiara author Didic Mira author Festari Cristina author Nicolosi Valentina author Sacco Leonardo author Aerts Liesbeth author Albanese Emiliano 811015 author Annoni Gian-Maria 133986 author Ballhausen Nicola 802674 author Chicherio Christian 85466 author Démonet Jean‐François author Descloux Virginie 582295 author Diener Suzie author Ferreira Daniel author Georges Jean author Gietl Anton author Girtler Nicola author Kilimann Ingo author Klöppel Stefan author Kustyniuk Nicole author Mecocci Patrizia author Mella Nathalie 0000-0001-9578-5012 681280 author Pigliautile Martina author Seeher Katrin author Shirk Steven D. author Toraldo Alessio author Brioschi‐Guevara Andrea author Chan Kwun C. G. author Crane Paul K. author Dodich Alessandra 896999 author Grazia Alice author Kochan Nicole A author Oliveira Fabricio Ferreira author Nobili Flavio author Kukull Walter author Peters Oliver author Ramakers Inez author Sachdev Perminder S. author Teipel Stefan author Visser Pieter Jelle author Wagner Michael author Weintraub Sandra author Westman Eric author Froelich Lutz author Brodaty Henry author Dubois Bruno author Cappa Stefano F. author Salmon David author Winblad Bengt author Frisoni Giovanni 810190 author Kliegel Matthias 761733 the Consortium for the Harmonization of Neuropsychological Assessment for Neurocognitive Disorders 29-42 10.1002/alz.12365 33984176 1552-5260 PMC9642857 https://onlinelibrary.wiley.com/doi/10.1002/alz.12365 Introduction: Harmonized neuropsychological assessment for neurocognitive disorders, an international priority for valid and reliable diagnostic procedures, has been achieved only in specific countries or research contexts. Methods: To harmonize the assessment of mild cognitive impairment in Europe, a workshop (Geneva, May 2018) convened stakeholders, methodologists, academic, and non-academic clinicians and experts from European, US, and Australian harmonization initiatives. Results: With formal presentations and thematic working-groups we defined a standard battery consistent with the U.S. Uniform DataSet, version 3, and homogeneous methodology to obtain consistent normative data across tests and languages. Adaptations consist of including two tests specific to typical Alzheimer's disease and behavioral variant frontotemporal dementia. The methodology for harmonized normative data includes consensus definition of cognitively normal controls, classification of confounding factors (age, sex, and education), and calculation of minimum sample sizes. Discussion: This expert consensus allows harmonizing the diagnosis of neurocognitive disorders across European countries and possibly beyond. Alzheimer's disease Cognitive assessment Diagnosis Mild cognitive impairment Mild neurocognitive disorders Standard neuropsychological assessment Dewey 128.37 Dewey 616.89 Dewey 616.8 Dewey 616.0757 Dewey 150 Dewey 370 Dewey 618.97 European Commission Amyloid imaging to Prevent Alzheimer’s Disease – Sofia ref.: 115952 115952 AMYPAD EU H2020 Swiss National Science Foundation Harmonizing Neuropsychological Assessment for Dementia in Europe. IZSEZ0_180198 15 Centre interfacultaire en sciences affectives 0D8 60 Département de psychiatrie 225 108 Section de psychologie 71 109 Section des sciences de l'éducation 72 61 Département des neurosciences cliniques 226 62 Département de radiologie et informatique médicale 227 65 Département de réadaptation et gériatrie 22B false 593 Emergence et expression de l'émotion (E3 Lab) 643 Groupe de recherche en psychologie de la santé (GREPS) 1319 Genre - Rapports intersectionnels, Relation éducative (G-RIRE) 853 Troubles de mémoire et maladie d'Alzeimer 935 633 Cognitive Aging Lab (CAL) Alzheimer's & dementia 18 1 885b2965-75ff-4f1c-9395-ac18319c1630 Article (Published version) Public Alzheimer s Dementia - 2021 - Bocca.pdf 696425 application/pdf CC BY-NC-4.0 330abca2-3fcc-436e-9756-600cab9ebf1f Appendix Public alz12365-sup-0001-suppmat.docx 274342 application/vnd.openxmlformats-officedocument.wordprocessingml.document Supporting information openAccess Centres et instituts / Centre interfacultaire en sciences affectives Faculté de médecine / Section de médecine clinique / Département de psychiatrie Faculté de psychologie et des sciences de l'éducation / Section de psychologie Faculté de psychologie et des sciences de l'éducation / Section des sciences de l'éducation Faculté de médecine / Section de médecine clinique / Département des neurosciences cliniques Faculté de médecine / Section de médecine clinique / Département de radiologie et informatique médicale Faculté de médecine / Section de médecine clinique / Département de réadaptation et gériatrie

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