The predictive value of hypometabolism in focal epilepsy: a prospective study in surgical candidates

Article Article scientifique Article The predictive value of hypometabolism in focal epilepsy: a prospective study in surgical candidates eng 2019 author Tomas Aurin Josép 543350 author Pittau Francesca 812753 author Hammers Alexander author Bouvard Sandrine author Picard Fabienne 123049 author Vargas Gomez Maria Isabel 503296 author Sales Francisco author Seeck Margitta 133679 author Garibotto Valentina 0000-0003-2422-698X 704817 1806-1816 10.1007/s00259-019-04356-x 31144060 1619-7070 FDG PET is an established tool in presurgical epilepsy evaluation, but it is most often used selectively in patients with discordant MRI and EEG results. Interpretation is complicated by the presence of remote or multiple areas of hypometabolism, which leads to doubt as to the true location of the seizure onset zone (SOZ) and might have implications for predicting the surgical outcome. In the current study, we determined the sensitivity and specificity of PET localization prospectively in a consecutive unselected cohort of patients with focal epilepsy undergoing in-depth presurgical evaluation. Dewey 616.0757 Dewey 616.8 Swiss National Science Foundation 113766; 180365; 163398 CH 61 Département des neurosciences cliniques 226 62 Département de radiologie et informatique médicale 227 false 119 Epilepsie et Chirurgie 149 1222 Laboratoire de neuroimagerie et de traceurs moléculaires innovants 984 European Journal of Nuclear Medicine and Molecular Imaging 46 9 21712920-6232-41c1-bace-26955e24de7c Article (Published version) Restricted Tomás2019_Article_ThePredictiveValueOfHypometabo.pdf 1668507 application/pdf restrictedAccess Faculté de médecine / Section de médecine clinique / Département des neurosciences cliniques Faculté de médecine / Section de médecine clinique / Département de radiologie et informatique médicale

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The predictive value of hypometabolism in focal epilepsy: a prospective study in surgical candidates	European Journal of Nuclear Medicine and Molecular Imaging			2019	272	0

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Tomas Aurin, Josép