The role of sFlt1/PlGF ratio in the assessment of preeclampsia and pregnancy-related hypertensive disorders

Article Article scientifique Revue de la littérature The role of sFlt1/PlGF ratio in the assessment of preeclampsia and pregnancy-related hypertensive disorders eng 2021-07-14 2021-07-14 author Baert Jonathan author Mc Carey Catherine Grazia 583508 author Berkane Nadia author Martinez De Tejada Weber Begona 590919 author Vial Yvan author Rieder Wawrzyniec 540989 w20533 10.4414/smw.2021.20533 34283894 0036-7672 https://smw.ch/index.php/smw/article/view/3030 Preeclampsia is a major cause of maternal and fetal morbidity and mortality. Early recognition of the disease may be challenging. Complications may precede the onset of clinical symptoms and medical intervention is often delayed. Moreover, in the absence of specific clinical signs, many patients will present symptoms mimicking the disease without ever being diagnosed with preeclampsia. This situation may, however, lead to medical interventions and cause unnecessary stress for the patient. For many years, research tried to evaluate the significance of serum biomarkers as early indicators of preeclampsia. Among many, the sFlt-1/PlGF ratio, given its performance, aroused the greatest interest. This article reviews current knowledge on the subject, focusing on a Swiss perspective. Biomarkers Female Humans Hypertension, Pregnancy-Induced / diagnosis Pre-Eclampsia / diagnosis Pregnancy Vascular Endothelial Growth Factor Receptor-1 Dewey 618 58 Département de pédiatrie, gynécologie et obstétrique 223 false 213 Martinez De Tejada Begona 272 Schweizerische medizinische Wochenschrift 151 9b38de88-bfe6-4d75-ad18-e5c9170a788f Article (Published version) Public Assessment of preeclampsia.pdf 471505 application/pdf CC BY-NC-ND-4.0 openAccess Faculté de médecine / Section de médecine clinique / Département de pédiatrie, gynécologie et obstétrique

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The role of sFlt1/PlGF ratio in the assessment of preeclampsia and pregnancy-related hypertensive disorders	Schweizerische medizinische Wochenschrift			2021	133	254

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