Cognitive behavioural therapy for weight gain associated with antipsychotic drugs

Article Article scientifique Article Cognitive behavioural therapy for weight gain associated with antipsychotic drugs eng 2007 author Khazaal Yasser 668423 author Fresard Emmanuelle 506756 author Rabia Sophie 517111 author Chatton Anne 54835 author Rothen Stéphane 691816 author Pomini Valentino author Grasset François author Borgeat François author Zullino Daniele Fabio 649976 169-177 10.1016/j.schres.2006.12.025 17306507 0920-9964 Overweight and obesity are common concerns in individuals with severe mental disorders. In particular, antipsychotic drugs (AP) frequently induce weight gain. This phenomenon lacks current management and no previous controlled studies seem to use cognitive therapy to modify eating and weight-related cognitions. Moreover, none of these studies considered binge eating or eating and weight-related cognitions as possible outcomes. The main aim of this study is to assess the effectivity of cognitive and behavioural treatment (CBT) on eating and weight-related cognitions, binge eating symptomatology and weight loss in patients who reported weight gain during AP treatment. A randomized controlled study (12-week CBT vs. Brief Nutritional Education) was carried out on 61 patients treated with an antipsychotic drug who reported weight gain following treatment. Binge eating symptomatology, eating and weight-related cognitions, as well as weight and body mass index were assessed before treatment, at 12 weeks and at 24 weeks. The CBT group showed some improvement with respect to binge eating symptomatology and weight-related cognitions, whereas the control group did not. Weight loss occurred more progressively and was greater in the CBT group at 24 weeks. The proposed CBT treatment is particularly interesting for patients suffering from weight gain associated with antipsychotic treatment. Antipsychotic drugs Olanzapine Clozapine Weight gain Obesity Binge eating disorder Cognitive and behavioural therapy Dewey 330 Dewey 616.89 Dewey 310 60 Département de psychiatrie 225 117 Research Center for Statistics S5 false 496 Abus de substances 834 Schizophrenia research 91 1-3 363d33cc-2c38-4e54-95a2-ed19edfd0c1d Article (Published version) Restricted 2007_Khazaal_Cognitive_SR.pdf 251996 application/pdf restrictedAccess Faculté de médecine / Section de médecine clinique / Département de psychiatrie Faculté d'économie et de management / Research Center for Statistics

Title	Published in	Access level	OA Policy	Year	Views	Downloads

Cognitive behavioural therapy for weight gain associated with antipsychotic drugs	Schizophrenia research			2007	704	0

Archive ouverte UNIGE

Rabia, Sophie