Synthesis of Multiply Substituted, Ion Channel Forming Octi(p-phenylene)s: Theme and Variations

Article Article scientifique Lettre Synthesis of Multiply Substituted, Ion Channel Forming Octi(p-phenylene)s: Theme and Variations eng 2000 author Robert Fabien 126547 author Winum Jean-Yves 514501 author Sakai Naomi 131140 author Gerard David 27973 author Matile Stefan 0000-0002-8537-8349 129654 37-39 10.1021/ol991210n 10814240 1523-7052 To facilitate the access to unique models for biological processes, we examined six different synthetic routes to octi(p-phenylene) rods with lateral and terminal substituents R(L) and R(T). This systematic study allowed us to increase to overall yield for the synthesis of a new class of oligo(p-phenylene) ionophores about 20 times and to provide general insights into the practicability of synthetic routes to multiply substituted molecular rods. Dewey 540 true Organic letters 2 1 d64ba3f0-0734-41fe-abbc-a666ca7f1047 Article Restricted file1.pdf 87919 application/pdf Vignette Public file2.gif 3828 image/gif restrictedAccess

Title	Published in	Year	Views	Downloads

Synthesis of Multiply Substituted, Ion Channel Forming Octi(p-phenylene)s: Theme and Variations	Organic letters	2000	653	3
Rigid Push-Pull Oligo(p-Phenylene) Rods: Depolarization of Bilayer Membranes with Negative Membrane Potential	Journal of the American Chemical Society	1999	640	1

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Winum, Jean-Yves