The Effects of Shift Work on Cardio-Metabolic Diseases and Eating Patterns

Article Article scientifique Revue de la littérature The Effects of Shift Work on Cardio-Metabolic Diseases and Eating Patterns eng 2021-11-22 2021-11-22 author Hemmer Alexandra 701337 author Mareschal Julie 861080 author Dibner Charna 0000-0002-4188-803X 583541 author Pralong Jacques-André 510876 author Dorribo Victor 512377 author Perrig Stephen 550927 author Genton Graf Laurence 0000-0002-0037-5203 514243 author Pichard Claude 21908 author Collet Tinh-Hai 0000-0002-3243-1222 935563 4178 10.3390/nu13114178 34836433 2072-6643 PMC8617838 https://www.mdpi.com/2072-6643/13/11/4178 Energy metabolism is tightly linked with circadian rhythms, exposure to ambient light, sleep/wake, fasting/eating, and rest/activity cycles. External factors, such as shift work, lead to a disruption of these rhythms, often called circadian misalignment. Circadian misalignment has an impact on some physiological markers. However, these proxy measurements do not immediately translate into major clinical health outcomes, as shown by later detrimental health effects of shift work and cardio-metabolic disorders. This review focuses on the effects of shift work on circadian rhythms and its implications in cardio-metabolic disorders and eating patterns. Shift work appears to be a risk factor of overweight, obesity, type 2 diabetes, elevated blood pressure, and the metabolic syndrome. However, past studies showed discordant findings regarding the changes of lipid profile and eating patterns. Most studies were either small and short lab studies, or bigger and longer cohort studies, which could not measure health outcomes in a detailed manner. These two designs explain the heterogeneity of shift schedules, occupations, sample size, and methods across studies. Given the burden of non-communicable diseases and the growing concerns about shift workers’ health, novel approaches to study shift work in real contexts are needed and would allow a better understanding of the interlocked risk factors and potential mechanisms involved in the onset of metabolic disorders. Cardiovascular disease Circadian misalignment Eating patterns Metabolic disease Shift work Dewey 612 Dewey 616 56 Département de médecine 221 134 Département de physiologie cellulaire et métabolisme 21C false 1386 Nutrition et chronobiologie 1038 913 Endocrinologie et horloge circadienne 948 Nutrients 13 11 e6710ea6-d343-42b3-ad4a-16e47108b97f Article (Published version) Public nutrients-13-04178.pdf 291350 application/pdf CC BY-4.0 openAccess Faculté de médecine / Section de médecine clinique / Département de médecine Faculté de médecine / Section de médecine fondamentale / Département de physiologie cellulaire et métabolisme

Title	Published in	Access level	OA Policy	Year	Views	Downloads

The Effects of Shift Work on Cardio-Metabolic Diseases and Eating Patterns	Nutrients			2021	348	390

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Dorribo, Victor