The effects of hypothermic cardiopulmonary bypass on Doppler cerebral blood flow during the first 24 postoperative hours

Article Article scientifique Article The effects of hypothermic cardiopulmonary bypass on Doppler cerebral blood flow during the first 24 postoperative hours eng 2003-03 author Bendjelid Karim 0000-0002-7921-7207 Division of Surgical Intensive Care, Department APSIC, University Hospitals of Geneva, CH-1211 Geneva 14, Switzerland. karim.bendjelid@hcuge.ch 527948 Département d'anesthésiologie, pharmacologie et soins intensifs (APSIC) author Poblete-Schuhmann Beate 500554 author Baenziger Oskar author Romand Jacques-André 121831 46-52 10.1016/S1569-9293(02)00098-1 17669986 1569-9285 https://academic.oup.com/icvts/article/2/1/46/657741 To provide understanding of influence of cardiopulmonary bypass (CPB) on cerebral blood flow (CBF), we investigated the effect of CPB on patients' cerebral haemodynamic parameters. Twenty-three patients were prospectively enrolled. CBF was estimated by transcranial Doppler (TCD) to measure blood velocity in the middle cerebral artery (MVMCA), preoperatively T(0) and at four postoperative times (T(1), T(2), T(3), T(4)). At times T(2), T(3) and T(4), MVMCA remained at higher levels than T(0) (P < 0.05). In the multivariate analysis PaCO(2) was independently associated to MVMCA at times T(1) and T(2) (P = 0.03, P = 0.01, respectively) and temperature was independently associated with MVMCA at time T(1) (P = 0.02). Thus, the present study showed an increase in CBF after CPB, that was correlated with raised temperature but not with decrease in haematocrit. Coronary artery bypass grafting Human clinical study Heart surgery Rewarming Dewey 617 63 Département d'anesthésiologie, pharmacologie, soins intensifs et urgences 229 false 570 Groupe de recherche en hémodynamique 913 Interactive cardiovascular and thoracic surgery 2 1 11065df1-ce76-4471-bf02-9c5f725bec80 Article (Published version) Public CBF.pdf 139687 application/pdf 4e5ec7b7fd90259d946f43ec7497653e84c239afc53d0a933884f9dd824ec57c openAccess Faculté de médecine / Section de médecine clinique / Département d'anesthésiologie, pharmacologie, soins intensifs et urgences

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The effects of hypothermic cardiopulmonary bypass on Doppler cerebral blood flow during the first 24 postoperative hours	Interactive cardiovascular and thoracic surgery			2003	45	21

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Poblete-Schuhmann, Beate