The developmental neural substrates of Hebb repetition learning and their link with reading ability

Article Article scientifique Article The developmental neural substrates of Hebb repetition learning and their link with reading ability eng 2020-06-23 2020-10 author Attout Lucie 0000-0002-4494-9379 Psychology and Neuroscience of Cognition Research Unit, University of Liège, Liège, Belgium.,Fund for Scientific Research FNRS, Brussels, Belgium. 432435 Section de psychologie (PSICO) author Ordonez Magro Laura Psychological Sciences Research Institute, Université catholique de Louvain, Louvain-la-Neuve, Belgium. 444053 Section de psychologie (PSICO) author Szmalec Arnaud 0000-0003-3903-3953 Psychological Sciences Research Institute, Université catholique de Louvain, Louvain-la-Neuve, Belgium.,Department of Experimental Psychology, Ghent University, Ghent, Belgium. author Majerus Steve Psychology and Neuroscience of Cognition Research Unit, University of Liège, Liège, Belgium.,Fund for Scientific Research FNRS, Brussels, Belgium. 3956-3969 10.1002/hbm.25099 32573904 1065-9471 PMC7469830 https://onlinelibrary.wiley.com/doi/10.1002/hbm.25099 Hebb repetition learning is a fundamental learning mechanism for sequential knowledge, such as language. However, still little is known about its development. This fMRI study examined the developmental neural substrates of Hebb repetition learning and its relation with reading abilities in a group of 49 children aged from 6 to 12 years. In the scanner, the children carried out an immediate serial recall task for syllable sequences of which some sequences were repeated several times over the course of the session (Hebb repetition sequences). The rate of Hebb repetition learning was associated with modulation of activity in the medial temporal lobe. Importantly, for the age range studied here, learning-related medial temporal lobe modulation was independent of the age of the children. Furthermore, we observed an association between regular and irregular word reading abilities and the neural substrates of Hebb repetition learning. This study suggests that the functional neural substrates of Hebb repetition learning do not undergo further maturational changes in school age children, possibly because they are sustained by implicit sequential learning mechanisms which are considered to be fully developed by that age. Importantly, the neural substrates of Hebb learning remain significant determinants of children's learning abilities, such as reading. Hebb repetition language Development FMRI Language Learning Reading Serial order Fonds De La Recherche Scientifique - FNRS T.1003.15‐PDR (FRFC) true Human brain mapping 41 14 0bdabb7e-deb1-43e1-950f-7bc86e386b6b Article (Published version) Public Attout_Ordonez_Magro_Szmalec_Majeru.pdf 1190680 application/pdf CC BY-NC-4.0 cc1f02f0fa725bb7afa47b3874a2843bc50acb3cd7a832ab0136e6e4c4bcc995 openAccess

Title	Published in	Access level	OA Policy	Year	Views	Downloads

The developmental neural substrates of Hebb repetition learning and their link with reading ability	Human brain mapping			2020	15	65

Archive ouverte UNIGE

Ordonez Magro, Laura