Oncoplastic reduction mammoplasty : systematic review and proportional meta-analysis of surgical outcomes

Article Article scientifique Revue de la littérature Oncoplastic reduction mammoplasty : systematic review and proportional meta-analysis of surgical outcomes eng 2023-12-05 2024-02 author Tekdogan Boran-Can Department of Plastic, Reconstructive, and Aesthetic Surgery, Geneva University Hospitals, Geneva University, 1205 Geneva, Switzerland. 416947 author Martineau Jerôme Department of Plastic, Reconstructive, and Aesthetic Surgery, Geneva University Hospitals, Geneva University, 1205 Geneva, Switzerland. author Scampa Matteo 0000-0003-0461-7596 Department of Plastic, Reconstructive, and Aesthetic Surgery, Geneva University Hospitals, Geneva University, 1205 Geneva, Switzerland. 751050 author Kalbermatten Daniel Department of Plastic, Reconstructive, and Aesthetic Surgery, Geneva University Hospitals, Geneva University, 1205 Geneva, Switzerland. 948183 Département de chirurgie (CHIRU) Daniel Felix Kalbermatten author Oranges Carlo Department of Plastic, Reconstructive, and Aesthetic Surgery, Geneva University Hospitals, Geneva University, 1205 Geneva, Switzerland. Electronic address: carlo.oranges@hcuge.ch. 955344 Département de chirurgie (CHIRU) 86-96 10.1016/j.bjps.2023.11.052 38159475 1748-6815 https://www.sciencedirect.com/science/article/pii/S174868152300774X Background: Breast-conserving surgery is the standard of care for early-stage breast cancer but can often result in unsatisfactory cosmetic outcomes. Oncoplastic surgery aims to address these issues by combining local excision with plastic surgery techniques to improve oncologic and esthetic outcomes. By incorporating breast reduction techniques into cancer surgery, wider margins of excision can be achieved, leading to enhanced oncological safety and reduced recurrence rates without causing significant asymmetry. This systematic review and meta-analysis aims to provide an updated understanding of the surgical outcomes associated with oncoplastic reduction mammoplasty. Methods: A systematic review of the literature was conducted according to PRISMA guidelines. Articles reporting post-operative outcomes following the oncoplastic reduction mammoplasty were included. A proportional meta-analysis of post-operative complications was performed to obtain their proportions and 95% Confidence Intervals (CIs). Results: Eighteen studies met the inclusion criteria, representing a total of 2711 oncoplastic reduction mammoplasty procedures in 2680 patients. The overall complication rate was 20% (95% CI: 15-25%). The positive margin rate following oncoplastic reduction mammoplasty was 11% (95% CI: 6-17%). The re-excision rate was 6% (95% CI: 3-12%). The completion mastectomy rate was 3% (95% CI: 2-6%). Conclusions: Oncoplastic reduction mammoplasty is a safe and effective alternative to mastectomy and traditional breast-conserving surgery in the treatment of early-stage breast cancers. Breast Breast cancer Breast reduction Oncoplastic mammoplasty Proportional meta-analysis Reconstruction Humans Female Mastectomy Breast Neoplasms / surgery Breast Neoplasms / etiology Mammaplasty / methods Breast / surgery Mastectomy, Segmental / adverse effects Mastectomy, Segmental / methods Treatment Outcome Dewey 617 57 Département de chirurgie 222 false 1343 Reconstruction chirurgicale et régénération des tissus 1029 Journal of plastic, reconstructive & aesthetic surgery 89 6f1d58b5-b38b-4ad9-970b-8e6f8ef1019c Article (Published version) Restricted 1-s2.0-S174868152300774X-main.pdf 1296455 application/pdf 3d8b3779dc5e7ac3c724f0e650c7ded196cdca8a923bfacce45a8e48e63a0599 2760ae06-853f-4b41-9a49-fd8a76ab6aeb Supplemental data Restricted ScienceDirect_files_02Apr2024_14-25.zip 2120296 application/zip 91358dbf2397725063d5e43270ebb6d73ee985e099104e25b3def8b4c026c00b restrictedAccess Faculté de médecine / Section de médecine clinique / Département de chirurgie

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Oncoplastic reduction mammoplasty : systematic review and proportional meta-analysis of surgical outcomes	Journal of plastic, reconstructive & aesthetic surgery			2024	83	0

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