A vascular smooth muscles nitric oxide relaxation by a mechanism distinct of calcium changes

Article Article scientifique Article A vascular smooth muscles nitric oxide relaxation by a mechanism distinct of calcium changes eng 1994-01 author Chabaud Fabienne 24488 author Danna Mireille Béatrice 40598 author Beny Jean-Louis 26368 1449-1458 10.1016/0024-3205(94)00600-8 0024-3205 https://linkinghub.elsevier.com/retrieve/pii/0024320594006008 Prostaglandin F2α contracts coronary arteries smooth muscles under conditions of extra cellular and intracellular calcium depletion. In these conditions, nitrogen-oxide-containing vasodilators or natural EDRF(s) released by the kinins, substance P and bradykinin, from the endothelium relax strips of pig coronary arteries. This indicates that nitric oxide not only needs to lower cytosolic free calcium to relaxes the smooth muscles, but in addition another mechanism, independent of cytosolic calcium changes, is necessary to fully relax strips contracted by Prostaglandin F2α. Calcium Coronary artery Smooth muscle Nitric oxide Vascular relaxation Dewey 590 44 Département de génétique et évolution 162 false Life sciences 54 19 0bdbb22f-97da-4eb4-bcbd-5625533790b3 Article (Published version) Restricted Chabaud_LS_1994541449.pdf 4284434 application/pdf restrictedAccess Faculté des sciences / Section de biologie / Département de génétique et évolution

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A vascular smooth muscles nitric oxide relaxation by a mechanism distinct of calcium changes	Life sciences			1994	196	0

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Danna, Mireille Béatrice