La transplantation hépatique. Expérience préliminaire de l'Hôpital cantonal universitaire de Genève

Article Article scientifique Article La transplantation hépatique. Expérience préliminaire de l'Hôpital cantonal universitaire de Genève fre 1990 author Mentha Gilles 22892 author Meyer Pierre 27012 author Huber Olivier 50133 author Le Coultre Claude Pierrette 24018 author Villiger Alain 75516 author Cereda Jean-Michel 527039 author Widmann Jean-Jacques 73624 author Pittet Didier 117792 author Gunn-sechehaye Alexis Claude Michel 33638 author Schneider P 1037-1044 2374894 0036-7672 Between July 1987 and May 1989, 11 liver transplants were performed on 10 patients at the University Hospital of Geneva. Of 15 patients evaluated for elective transplantation, 10 were accepted and put on the waiting list. 5 patients were rejected because of a contraindication or because another treatment seemed preferable. 8 transplantations were eventually performed. Emergency transplantation was considered for 6 patients, but could be performed in only 3. Indications for transplantation were as follows: one hepatocellular carcinoma in a non-cirrhotic patient, 2 post-hepatitis cirrhoses (one B and one non-A-, non-B), 3 primary biliary cirrhoses, one autoimmune cirrhosis, one primary sclerosing cholangitis, one cirrhosis on alpha-1-antitrypsin deficiency, and one fulminant B-Delta hepatitis. Most of these patients had advanced liver disease and a limited life expectancy. 8 of the 10 patients transplanted are nevertheless alive and none is hospitalized at the present time. More than mere survival, however, quality of life regained after transplantation prompts us to consider transplantation early in the progress of the disease. Earlier evaluation of patients would make transplantation feasible soon after the first complication of the disease. This attitude would probably prevent patients from dying while on a waiting list and decrease operative as well as early postoperative risks. Better information and coordination regarding potential donors is necessary in Switzerland to obtain better results in organ transplantation. Adult Cholangitis, Sclerosing/surgery Emergencies Female Humans Immunosuppression Length of Stay Liver Cirrhosis/surgery Liver Transplantation Male Middle Aged Postoperative Complications/etiology Dewey 576.5 Dewey 617 135 Département de médecine génétique et développement 21D 57 Département de chirurgie 222 false 79 Chirurgie viscérale 104 1329 Chirurgie viscérale (HUG) 249 Hépatologie chirurgicale 327 251 Staphylocoques dorés résistants à la méthicilline et hygiène hospitalière 330 Schweizerische medizinische Wochenschrift 120 29 Faculté de médecine / Section de médecine fondamentale / Département de médecine génétique et développement Faculté de médecine / Section de médecine clinique / Département de chirurgie

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La transplantation hépatique. Expérience préliminaire de l'Hôpital cantonal universitaire de Genève	Schweizerische medizinische Wochenschrift			1990	805	0

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Gunn-sechehaye, Alexis Claude Michel