HPLC separation of catecholamines after derivatization with 9-fluorenylmethyl chloroformate

Article Article scientifique Article HPLC separation of catecholamines after derivatization with 9-fluorenylmethyl chloroformate eng 1992 author Descombes Antoine Alexandre 31102 author Haerdi Werner 24913 83-86 10.1007/BF02276857 0009-5893 http://link.springer.com/10.1007/BF02276857 Optimum conditions for the separation of 9-fluorenylmethyl chloroformate derivatized catecholamines by HPLC are described; three catecholamines (noradrenaline, adrenaline and dopamine) and an internal standard (epinine) were separated in less than 20 minutes under isocratic conditions. This method is 17 to 350 times more sensitive than electrochemical detection, depending on the test compounds. It has been applied to the analysis of catecholamines in urine. The sample was extracted by a metal-loaded silica prior to separation. Column liquid chromatography Pre-derivatization Catecholamines 9-fluorenylmethyl chloroformate (FMOC-Cl) Dewey 540 40 Département de chimie minérale, analytique et appliquée 145 false Chromatographia 33 1-2 4f2b7d70-1658-4d15-a8ce-72fbaab4fc8f Article (Published version) Restricted AA.Descombes.pdf 363037 application/pdf restrictedAccess Faculté des sciences / Section de chimie et biochimie / Département de chimie minérale, analytique et appliquée

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HPLC separation of catecholamines after derivatization with 9-fluorenylmethyl chloroformate	Chromatographia			1992	583	1

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Descombes, Antoine Alexandre