Towards a multidisciplinary approach to understand and manage obesity and related diseases

Article Article scientifique Article Towards a multidisciplinary approach to understand and manage obesity and related diseases fre 2017 author Bischoff Stephan C. author Boirie Yves author Cederholm Tommy author Chourdakis Michael author Cuerda Cristina author Delzenne Nathalie M. author Deutz Nicolaas E. author Fouque Denis author Genton Graf Laurence 0000-0002-0037-5203 514243 author Gil Marquez Carmen 517115 author Koletzko Berthold author Leon-Sanz Miguel author Shamir Raanan author Singer Joelle author Singer Pierre author Stroebele-Benschop Nanette author Thorell Anders Erik 28509 author Weimann Arved author Barazzoni Rocco 917-938 10.1016/j.clnu.2016.11.007 27890486 0261-5614 https://linkinghub.elsevier.com/retrieve/pii/S0261561416313231 Overnutrition and sedentary lifestyle result in overweight or obesity defined as abnormal or excessive fat accumulation that may impair health. According to the WHO, the worldwide prevalence of obesity nearly doubled between 1980 and 2008. In 2008, over 50% of both men and women in the WHO European Region were overweight, and approximately 23% of women and 20% of men were obese. Comprehensive diagnostic and therapeutic approaches should include nutritional treatment to favor the best metabolic and nutritional outcome, as well as to induce potential disease-specific benefits from selected nutritional regimens. Obesity is usually accompanied by an increased muscle mass. This might explain why obesity, under particular circumstances such as cancer or high age, might have protective effects, a phenomenon named the ‘obesity paradox'. However, loss of muscle mass or function can also occur Sarcopenic obesity Metabolic syndrome Microbiota Fatty liver disease Dewey 616 56 Département de médecine 221 false 331 Nutrition clinique 597 Clinical Nutrition 36 4 6caf38a6-a2f4-4e1b-92c7-f62bb5d1386e Article (Accepted version) Public 1-s2.0-S0261561416313231-main.pdf 1777740 application/pdf openAccess Faculté de médecine / Section de médecine clinique / Département de médecine

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Towards a multidisciplinary approach to understand and manage obesity and related diseases	Clinical Nutrition			2017	463	1,970

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Thorell, Anders Erik