Differential effects of griseofulvin and benomyl on morphology and nuclear distribution during the germination of <i>Neurospora crassa</i> macroconidia

Article Article scientifique Article Differential effects of griseofulvin and benomyl on morphology and nuclear distribution during the germination of <i>Neurospora crassa</i> macroconidia eng 1992 author Barja François 26490 author Jaramillo-Maranon Maria Lucia 24635 author Rossier Claude 24796 author Turian Gilbert 25056 147-150 10.1016/S0953-7562(09)80931-3 0953-7562 https://linkinghub.elsevier.com/retrieve/pii/S0953756209809313 Griseofulvin caused concentration-dependent morphogenetic effects on the germination of macroconidia of Neurospora crassa. At 10–50 m, the germ tubes were typically sinuous. At 100–200 m, the compound induced multiple germ tube formation. Benomyl only slightly inhibited germination at low concentrations (0·25–0·5 m) and did not induce a sinuous pattern of germ tube elongation. It induced multipolar germination at 1–2 m. The analysis by DAPI fluorescence of the positioning of nuclei during germination revealed that benomyl, but not griseofulvin, prevented nuclear migration into multiple germ tubes. The aberrations of development induced by the two microtubule inhibitors were mediated without major changes in the N. crassa α- or β-tubulins. Dewey 580 45 Département des sciences végétales 163 false Mycological Research 96 2 8fdfc4cb-233e-4682-8a40-1ab2c8232401 Article (Published version) Restricted Barja_MR_199296147.pdf 315854 application/pdf restrictedAccess Faculté des sciences / Section de biologie / Département des sciences végétales

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Differential effects of griseofulvin and benomyl on morphology and nuclear distribution during the germination of Neurospora crassa macroconidia	Mycological Research			1992	431	0

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Jaramillo-Maranon, Maria Lucia