2.5 million annual deaths-are neonates in low- and middle-income countries too small to be seen ? A bottom-up overview on neonatal morbi-mortality

Article Article scientifique Revue de la littérature 2.5 million annual deaths-are neonates in low- and middle-income countries too small to be seen ? A bottom-up overview on neonatal morbi-mortality eng 2022-04-21 2022-04-21 author Rosa Mangeret Flavia 0000-0003-0908-6237 Neonatal Division, Geneva University Hospitals, 1205 Geneva, Switzerland.,Global Health Institute, University of Geneva, 1205 Geneva, Switzerland.,Faculty of Medicine, University of Geneva, 1205 Geneva, Switzerland. 830633 author Benski Anne-Caroline Obstetrics Division, Geneva University Hospitals, 1205 Geneva, Switzerland.,Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA. 862711 author Golaz Anne Center for Education and Research in Humanitarian Action, Faculty of Medicine, University of Geneva, 1205 Geneva, Switzerland. 23401 author Zala Persis Zokara 0000-0001-7137-7532 Neonatal Division, Geneva University Hospitals, 1205 Geneva, Switzerland.,Faculty of Medicine, University of Geneva, 1205 Geneva, Switzerland.,Centre Medico-Chirurgical-Pédiatrique Persis, Ouahigouya BP267, Burkina Faso. 930663 author Kyokan Michiko 0000-0001-5539-1828 Global Health Institute, University of Geneva, 1205 Geneva, Switzerland. 952365 author Wagner Noémie Pediatric Infectious Diseases Division, Geneva University Hospitals, 1205 Geneva, Switzerland. 512044 author Muhe Lulu M 0000-0002-2776-9923 College of Health Sciences, Addis Ababa University, Addis Ababa 1000, Ethiopia. author Pfister Riccardo 0000-0002-7395-0512 Neonatal Division, Geneva University Hospitals, 1205 Geneva, Switzerland.,Faculty of Medicine, University of Geneva, 1205 Geneva, Switzerland. 527070 Département de Pédiatrie, Gynécologie et Obstétrique (PETRI) 64 10.3390/tropicalmed7050064 35622691 2414-6366 PMC9148074 Background: Every year, 2.5 million neonates die, mostly in low- and middle-income countries (LMIC), in total disregard of their fundamental human rights. Many of these deaths are preventable. For decades, the leading causes of neonatal mortality (prematurity, perinatal hypoxia, and infection) have been known, so why does neonatal mortality fail to diminish effectively? A bottom-up understanding of neonatal morbi-mortality and neonatal rights is essential to achieve adequate progress, and so is increased visibility. Methods: We performed an overview on the leading causes of neonatal morbi-mortality and analyzed the key interventions to reduce it with a bottom-up approach: from the clinician in the field to the policy maker. Results and Conclusions: Overall, more than half of neonatal deaths in LMIC are avoidable through established and well-known cost-effective interventions, good quality antenatal and intrapartum care, neonatal resuscitation, thermal care, nasal CPAP, infection control and prevention, and antibiotic stewardship. Implementing these requires education and training, particularly at the bottom of the healthcare pyramid, and advocacy at the highest levels of government for health policies supporting better newborn care. Moreover, to plan and follow interventions, better-quality data are paramount. For healthcare developments and improvement, neonates must be acknowledged as humans entitled to rights and freedoms, as stipulated by international law. Most importantly, they deserve more respectful care. Neonatal morbidity Neonatal mortality Neonatal rights Dewey 613 Dewey 618 58 Département de pédiatrie, gynécologie et obstétrique 223 66 Institut de santé globale 22A1 false 424 Réanimation néonatale en salle d'accouchement 696 Tropical medicine and infectious disease 7 5 828502d6-5265-4107-bc3b-a3e4e0ef1ccf Article (Published version) Public Article-scientifique-from-unpaywall.pdf 433335 application/pdf CC BY-4.0 31472fb5041f606c91eef4da0fdab935da7e2970bc914c7f84c651955669c999 openAccess Faculté de médecine / Section de médecine clinique / Département de pédiatrie, gynécologie et obstétrique Faculté de médecine / Section de médecine clinique / Département de santé et médecine communautaires / Institut de santé globale

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2.5 million annual deaths-are neonates in low- and middle-income countries too small to be seen ? A bottom-up overview on neonatal morbi-mortality	Tropical medicine and infectious disease			2022	94	512

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Golaz, Anne