Normal values of signal-averaged electrocardiographic parameters and QT dispersion in infants and children

Article Article scientifique Article Normal values of signal-averaged electrocardiographic parameters and QT dispersion in infants and children eng 1999 author Vialle Emmanuelle 109909 author Albalkhi Rim 503949 author Zimmermann Marc 22840 author Friedli Beat 25332 556-561 10.1017/s1047951100005588 10593264 1047-9511 Ventricular late potentials, and dispersion of the QT interval, are markers for risk of ventricular arrhythmias. Normal values for these parameters are well established in adults, but may not apply for children. This study has investigated the age dependency of signal averaged electrocardiographic parameters and QT dispersion in 111 normal children aged from 5 days to 16 years. The results indicate that parameters change with age: duration of filtered QRS and low amplitude (< 40 microV) terminal signal increase with age, especially in the younger patients. Filtered QRS is 88.9 +/- 7.87 ms in infants, and increases to 108.7 +/- 8.51 in teenagers (p<0.001). Low amplitude terminal signals are 17.0 +/- 3.44 ms in infants, and 24.5 +/- 5.64 ms in teenagers (p<0.001). Root mean square of the last 40 ms decreases with age, but remains stable after the age of 10 years (122.4 +/- 33.30 microV in infants, 60.9 +/- 31.27 in teenagers, p<0.001). QT dispersion, on the other hand, does not change significantly with age. The mean value for the whole group is 36 +/- 13.7 ms. A weak but significant correlation exists between QT dispersion and filtered QRS. Thus, age must be taken into consideration when interpreting signal-averaged electrocardiograms, but not when measuring QT dispersion. Action Potentials Adolescent Age Factors Child Child, Preschool Electrocardiography Female Heart Conduction System/physiopathology Humans Infant Infant, Newborn Male Reference Values Signal Processing, Computer-Assisted Dewey 618 58 Département de pédiatrie, gynécologie et obstétrique 223 false Cardiology in the young 9 6 689052e9-062a-42a5-8e6a-4b49016587b9 Article (Published version) Restricted 556-561.pdf 1603589 application/pdf restrictedAccess Faculté de médecine / Section de médecine clinique / Département de pédiatrie, gynécologie et obstétrique

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Normal values of signal-averaged electrocardiographic parameters and QT dispersion in infants and children	Cardiology in the young			1999	570	0

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Vialle, Emmanuelle