Venous-arteriolar reflex in human gastrocnemius studied by NIRS

Article Article scientifique Article Venous-arteriolar reflex in human gastrocnemius studied by NIRS eng 2003 author Binzoni Tiziano 0009-0004-2592-7926 23000 author Ngo Loan 527028 author Girardis Massimo 109424 author Springett Roger author Terrier François 27166 author Delpy David 467-473 10.1007/978-1-4615-0075-9_44 14562742 0065-2598 Heat-up tilting manoeuvre from 0 to 60 degrees induces oxygenated and deoxygenated haemoglobin concentration changes in the human gastrocnemius. These changes, measured by NIRS, can only be partially explained by the blood volume displacement due to the gravitational force. In the present study it is demonstrated, by a dye dilution technique (indocyanine green), that a reduction in blood flow (venous-arteriolar and/or spinal reflex) is responsible of the limited oxyhaemoglobin concentration increase observed when going from 0 (2.54 +/- 0.48 blood flow in arbitrary units, a.u.) to 60 (1.46 +/- 0.55 a.u.) degrees. The proposed technique is potentially applicable to the detection of specific pathological aspects of microcirculation, such as arterial occlusion in the leg, diabetes mellitus, and congestive heart failure, where the venous-arteriolar reflex may be affected. Adult Arteries/physiology Humans Middle Aged Muscle, Skeletal/blood supply Spectroscopy, Near-Infrared/methods Veins/physiology Dewey 616.0757 Dewey 616.8 53 Département de neurosciences fondamentales 21A 62 Département de radiologie et informatique médicale 227 false 184 Groupe Binzoni Tiziano (radiologie) 234 Advances in experimental medicine and biology 530 Faculté de médecine / Section de médecine fondamentale / Département de neurosciences fondamentales Faculté de médecine / Section de médecine clinique / Département de radiologie et informatique médicale

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Venous-arteriolar reflex in human gastrocnemius studied by NIRS	Advances in experimental medicine and biology			2003	454	0

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Girardis, Massimo