Biphenyl-4-yl-acrylohydroxamic acids: Identification of a novel indolyl-substituted HDAC inhibitor with antitumor activity
Published inEuropean journal of medicinal chemistry, vol. 112, p. 99-105
Publication date2016
Abstract
Keywords
- Antineoplastic Agents/chemistry/pharmacology
- Apoptosis/drug effects
- Biphenyl Compounds/chemistry/pharmacology
- Colonic Neoplasms/drug therapy/metabolism
- Drug Screening Assays
- Antitumor
- HCT116 Cells
- Histone Deacetylase Inhibitors/chemistry/pharmacology
- Histone Deacetylases/metabolism
- Humans
- Hydroxamic Acids/chemistry/pharmacology
- Molecular Docking Simulation
- Neoplasms/drug therapy/metabolism
- Structure-Activity Relationship
Affiliation
Citation (ISO format)
CINCINELLI, Raffaella et al. Biphenyl-4-yl-acrylohydroxamic acids: Identification of a novel indolyl-substituted HDAC inhibitor with antitumor activity. In: European journal of medicinal chemistry, 2016, vol. 112, p. 99–105. doi: 10.1016/j.ejmech.2016.02.001
Main files (1)
Article (Published version)
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Identifiers
- PID : unige:94976
- DOI : 10.1016/j.ejmech.2016.02.001
- PMID : 26890116
ISSN of the journal0223-5234