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Title

Preference for CD4-guided versus continuous HARRT in Thailand

Authors
Ananworanich, Jintanat
Pumpradit, W.
Apateerapong, W.
Siangphoe, U.
Saenawat, S.
Phanuphak, P.
Published in AIDS Care. 2008, vol. 20, no. 3, p. 327-330
Abstract Nineteen patients who completed a 27-month CD4-guided structured treatment interruption (STI) trial that showed similar efficacy in STI and continuous arms were asked to choose CD4-guided versus continuous HAART after the study ended. Six chose STI and 13 chose continuous HAART. Reasons for not choosing STIs were fear of developing HIV-related illnesses (38%), fear of CD4 drop (30.8%), fear of viral load increase (7.7%) and ease (7.7%). Those who preferred CD4-guided HAART had a higher median CD4 count nadir during STI and fewer on-off cycles. This study provides an important insight into the preference of patients towards STI in a resource-limited setting.
Keywords AdultAnti-HIV Agents/ administration & dosageAntiretroviral Therapy, Highly Active/methodsCD4 Lymphocyte Count/ methodsDrug Administration ScheduleFemaleHIV Infections/ drug therapy/immunologyHumansMalePatient SatisfactionThailandTreatment OutcomeViral Load
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PMID: 18351480
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ANANWORANICH, Jintanat et al. Preference for CD4-guided versus continuous HARRT in Thailand. In: AIDS Care, 2008, vol. 20, n° 3, p. 327-330. https://archive-ouverte.unige.ch/unige:9286

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Deposited on : 2010-07-12

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