en
Scientific article
English

Preference for CD4-guided versus continuous HARRT in Thailand

Published inAIDS care, vol. 20, no. 3, p. 327-330
Publication date2008
Abstract

Nineteen patients who completed a 27-month CD4-guided structured treatment interruption (STI) trial that showed similar efficacy in STI and continuous arms were asked to choose CD4-guided versus continuous HAART after the study ended. Six chose STI and 13 chose continuous HAART. Reasons for not choosing STIs were fear of developing HIV-related illnesses (38%), fear of CD4 drop (30.8%), fear of viral load increase (7.7%) and ease (7.7%). Those who preferred CD4-guided HAART had a higher median CD4 count nadir during STI and fewer on-off cycles. This study provides an important insight into the preference of patients towards STI in a resource-limited setting.

Keywords
  • Adult
  • Anti-HIV Agents/ administration & dosage
  • Antiretroviral Therapy, Highly Active/methods
  • CD4 Lymphocyte Count/ methods
  • Drug Administration Schedule
  • Female
  • HIV Infections/ drug therapy/immunology
  • Humans
  • Male
  • Patient Satisfaction
  • Thailand
  • Treatment Outcome
  • Viral Load
Citation (ISO format)
ANANWORANICH, Jintanat et al. Preference for CD4-guided versus continuous HARRT in Thailand. In: AIDS care, 2008, vol. 20, n° 3, p. 327–330. doi: 10.1080/09540120701660304
Identifiers
ISSN of the journal0954-0121
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