Handling trial participants with missing outcome data when conducting a meta-analysis: a systematic survey of proposed approaches

Akl, Elie A; Kahale, Lara A; Agoritsas, Thomas; Brignardello-Petersen, Romina; Busse, Jason W; Carrasco-Labra, Alonso; Ebrahim, Shanil; Johnston, Bradley C; Neumann, Ignacio; Sola, Ivan; Sun, Xin; Vandvik, Per; Zhang, Yuqing; Alonso-Coello, Pablo; Guyatt, Gordon

doi:10.1186/s13643-015-0083-6

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Title		Handling trial participants with missing outcome data when conducting a meta-analysis: a systematic survey of proposed approaches
Authors		Akl, Elie A Kahale, Lara A Agoritsas, Thomas Brignardello-Petersen, Romina Busse, Jason W Carrasco-Labra, Alonso Ebrahim, Shanil Johnston, Bradley C Neumann, Ignacio Sola, Ivan Sun, Xin Vandvik, Per Zhang, Yuqing Alonso-Coello, Pablo Guyatt, Gordon show all authors [1 - 15]
Published in		Systematic Reviews. 2015, vol. 4, p. 98
Abstract		When potentially associated with the likelihood of outcome, missing participant data represents a serious potential source of bias in randomized trials. Authors of systematic reviews frequently face this problem when conducting meta-analyses. The objective of this study is to conduct a systematic survey of the relevant literature to identify proposed approaches for how systematic review authors should handle missing participant data when conducting a meta-analysis.
Keywords		Bias (Epidemiology) — Data Accuracy — Humans — Meta-Analysis as Topic — Patient Dropouts — Research Design/statistics & numerical data — Surveys and Questionnaires
Identifiers		DOI: 10.1186/s13643-015-0083-6 PMID: 26202162
Full text		Article (Published version) (441 Kb) - Free access
Structures		Faculté de médecine / Section de médecine clinique / Département de réadaptation et gériatrie
Research group		Epidémiologie clinique (115)
Citation (ISO format)		AKL, Elie A et al. Handling trial participants with missing outcome data when conducting a meta-analysis: a systematic survey of proposed approaches. In: Systematic Reviews, 2015, vol. 4, p. 98. doi: 10.1186/s13643-015-0083-6 https://archive-ouverte.unige.ch/unige:90344