en
Scientific article
Open access
English

Increase in bone mineral density after successful parathyroidectomy for tertiary hyperparathyroidism after renal transplantation

Published inWorld journal of surgery, vol. 32, no. 8, p. 1795-1801
Collection
  • Open Access - Licence nationale Springer
Publication date2008
Abstract

BACKGROUND: Few studies have reported changes of bone mineral density (BMD) after parathyroidectomy in patients with persistent hyperparathyroidism after renal transplantation (3 HPT). PATIENTS AND METHODS: We retrospectively analyzed 14 patients who underwent successful parathyroidectomy for 3 HPT and who had available BMD data before and after parathyroidectomy. RESULTS: Median follow-up time was 26 months (IQR: 16.8-40.2). Serum calcium levels decreased significantly after parathyroidectomy (2.32 +/- 0.09 versus 2.66 +/- 0.16 mmol/l; p < 0.01), as did PTH levels (5.1 +/- 3.0 versus 27.8 +/- 23.7 pmol/l; p < 0.01). Nine patients (64%) had a steroid-free immunosuppression at follow-up. Mean increase in BMD was 9.5 +/- 8.0% for the spine and 9.5 +/- 7.9% for the hip (p < 0.01 for both sites). Patients with osteoporosis (T-score

Keywords
  • Bone Density/physiology
  • Female
  • Humans
  • Hyperparathyroidism/etiology/physiopathology/surgery
  • Kidney Transplantation
  • Male
  • Middle Aged
  • Parathyroidectomy
  • Retrospective Studies
  • Treatment Outcome
Citation (ISO format)
COLLAUD, Stéphane et al. Increase in bone mineral density after successful parathyroidectomy for tertiary hyperparathyroidism after renal transplantation. In: World journal of surgery, 2008, vol. 32, n° 8, p. 1795–1801. doi: 10.1007/s00268-008-9495-y
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Article (Published version)
accessLevelPublic
Identifiers
ISSN of the journal0364-2313
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