Human skeletal myotubes display a cell-autonomous circadian clock implicated in basal myokine secretion

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Title		Human skeletal myotubes display a cell-autonomous circadian clock implicated in basal myokine secretion
Authors		Perrin, Laurent Loizides-Mangold, Ursula Skarupelova, Svetlana Pulimeno, Pamela Chanon, Stephanie Robert, Maud Bouzakri, Karim Modoux Losberger, Christine Roux-Lombard, Pascale Vidal, Hubert Lefai, Etienne Dibner, Charna show all authors [1 - 12]
Published in		Molecular metabolism. 2015, vol. 4, no. 11, p. 834-845
Abstract		Circadian clocks are functional in all light-sensitive organisms, allowing an adaptation to the external world in anticipation of daily environmental changes. In view of the potential role of the skeletal muscle clock in the regulation of glucose metabolism, we aimed to characterize circadian rhythms in primary human skeletal myotubes and investigate their roles in myokine secretion.
Identifiers		DOI: 10.1016/j.molmet.2015.07.009 PMID: 26629407
Full text		Article (Published version) (1.5 MB) - Limited access to UNIGE
Structures		Faculté de médecine / Section de médecine clinique / Département de médecine
Research group		Etude de l'activation des monocytes/macrophages et des polynucléaires neutrophiles (779)
Citation (ISO format)		PERRIN, Laurent et al. Human skeletal myotubes display a cell-autonomous circadian clock implicated in basal myokine secretion. In: Molecular metabolism, 2015, vol. 4, n° 11, p. 834-845. doi: 10.1016/j.molmet.2015.07.009 https://archive-ouverte.unige.ch/unige:87994