Enantioselective one-pot organocatalytic michael addition/gold-catalyzed tandem acetalization/cyclization

Browse by...

Deposit

Highlights

More informations

Title		Enantioselective one-pot organocatalytic michael addition/gold-catalyzed tandem acetalization/cyclization
Authors		Belot, Sebastian Pascal Vogt, Kim A. Besnard, Céline Krause, Norbert Alexakis, Alexandre
Published in		Angewandte Chemie: International Edition. 2009, vol. 48, no. 47, p. 8923-8926
Abstract		A one-pot process consisting of a Michael addition to a nitroenyne and a subsequent acetalization/cyclization is reported (see scheme; TMS=trimethylsilyl), which results in the formation of nitro-substituted tetrahydrofuranyl ethers with high diastereo- and enantioselectivities. Organocatalysis and gold catalysis are compatible and complementary in a one-pot process.
Identifiers		DOI: 10.1002/anie.200903905 PMID: 19847839
Full text		Article (Published version) - Limited access to UNIGE
Structures		Faculté des sciences / Section de chimie et biochimie / Département de chimie organique
Citation (ISO format)		BELOT, Sebastian Pascal et al. Enantioselective one-pot organocatalytic michael addition/gold-catalyzed tandem acetalization/cyclization. In: Angewandte Chemie: International Edition, 2009, vol. 48, n° 47, p. 8923-8926. https://archive-ouverte.unige.ch/unige:8103