Biphenol-based phosphoramidite ligands for the enantioselective copper-catalyzed conjugate addition of diethylzinc

Browse by...

Deposit

Highlights

More informations

Title		Biphenol-based phosphoramidite ligands for the enantioselective copper-catalyzed conjugate addition of diethylzinc
Authors		Alexakis, Alexandre Polet, Damien Rosset, Stéphane March, Sebastien
Published in		Journal of Organic Chemistry. 2004, vol. 69, no. 17, p. 5660-5667
Abstract		Phosphoramidite ligands, based on ortho-substituted biphenols and a chiral amine, induce high enantioselectivities (ee's up to 99%) in the copper-catalyzed conjugate addition of dialkylzinc reagents to a variety of Michael acceptors. Particularly, the best reported ee's were obtained for acyclic nitroolefins.
Identifiers		DOI: 10.1021/jo049359m PMID: 15307737
Full text		Article (Published version) - Limited access to UNIGE
Structures		Faculté des sciences / Section de chimie et biochimie / Département de chimie organique
Citation (ISO format)		ALEXAKIS, Alexandre et al. Biphenol-based phosphoramidite ligands for the enantioselective copper-catalyzed conjugate addition of diethylzinc. In: Journal of Organic Chemistry, 2004, vol. 69, n° 17, p. 5660-5667. doi: 10.1021/jo049359m https://archive-ouverte.unige.ch/unige:8031