en
Scientific article
English

1,4-Dichloro- and 1,4-Dibromo-2-butenes as Substrate for Cu-catalyzed Asymmetric Allylic Substitution

Published inAngewandte Chemie, vol. 46, no. 15, p. 2619-2622
Publication date2007
Abstract

Cu at the AAA meeting: Difunctionalized allylic substrates can undergo Cu-catalyzed asymmetric allylic alkylation (AAA) reactions with high enantioselectivities. The products have a functional group that remains for further transformation through substitution with a nucleophile (Nu) or electrophile (E) with conservation of optical purity (see scheme; TC=thiophene carboxylate).

Keywords
  • Alkylation
  • Allylic compounds
  • Asymmetric catalysis
  • Copper
  • Nucleophilic substitution
Citation (ISO format)
FALCIOLA, Caroline Alexandra, ALEXAKIS, Alexandre. 1,4-Dichloro- and 1,4-Dibromo-2-butenes as Substrate for Cu-catalyzed Asymmetric Allylic Substitution. In: Angewandte Chemie, 2007, vol. 46, n° 15, p. 2619–2622. doi: 10.1002/anie.200604963
Main files (1)
Article (Published version)
accessLevelRestricted
Identifiers
ISSN of the journal1433-7851
698views
0downloads

Technical informations

Creation06/21/2010 2:15:38 PM
First validation06/21/2010 2:15:38 PM
Update time03/14/2023 3:47:42 PM
Status update03/14/2023 3:47:42 PM
Last indexation01/15/2024 8:25:40 PM
All rights reserved by Archive ouverte UNIGE and the University of GenevaunigeBlack