en
Scientific article
English

Hyalurosome gene regulation and dose-dependent restoration of skin atrophy by retinaldehyde and defined-size hyaluronate fragments in dermatoporosis

Published inDermatology, vol. 229, no. 2, p. 110-115
Publication date2014
Abstract

Dermatoporosis is an emerging clinical condition caused by chronological skin aging, long-term sun exposure and chronic use of corticosteroids; however, genomic expression in dermatoporosis and the efficacy of different therapeutic approaches to prevent and treat dermatoporosis have not been investigated so far.

Keywords
  • Adjuvants, Immunologic/administration & dosage
  • Administration, Topical
  • Antigens, CD44/biosynthesis/genetics
  • Atrophy/pathology/ultrasonography
  • Biopsy
  • Cell Adhesion Molecules/biosynthesis/genetics
  • Dose-Response Relationship, Drug
  • Drug Therapy, Combination
  • Follow-Up Studies
  • Forearm
  • Gene Expression Regulation
  • Heparin-binding EGF-like Growth Factor/biosynthesis/genetics
  • Humans
  • Hyaluronic Acid/administration & dosage
  • Hyaluronoglucosaminidase/biosynthesis/genetics
  • Keratinocytes/metabolism
  • RNA, Messenger/genetics
  • Real-Time Polymerase Chain Reaction
  • Retinaldehyde/administration & dosage
  • Retrospective Studies
  • Skin/pathology/ultrasonography
  • Skin Diseases/diagnosis/genetics/metabolism
  • Time Factors
  • Treatment Outcome
Research group
Citation (ISO format)
NIKOLIC, Damjan S et al. Hyalurosome gene regulation and dose-dependent restoration of skin atrophy by retinaldehyde and defined-size hyaluronate fragments in dermatoporosis. In: Dermatology, 2014, vol. 229, n° 2, p. 110–115. doi: 10.1159/000362594
Main files (1)
Article (Published version)
accessLevelRestricted
Identifiers
ISSN of the journal1018-8665
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