en
Scientific article
Review
English

In vivo studies of brain development by magnetic resonance techniques

Publication date2000
Abstract

Understanding of the morphological development of the human brain has largely come from neuropathological studies obtained postmortem. Magnetic resonance (MR) techniques have recently allowed the provision of detailed structural, metabolic, and functional information in vivo on the human brain. These techniques have been utilized in studies from premature infants to adults and have provided invaluable data on the sequence of normal human brain development. This article will focus on MR techniques including conventional structural MR imaging techniques, quantitative morphometric MR techniques, diffusion weighted MR techniques, and MR spectroscopy. In order to understand the potential applications and limitations of MR techniques, relevant physical and biological principles for each of the MR techniques are first reviewed. This is followed by a review of the understanding of the sequence of normal brain development utilizing these techniques. MRDD Research Reviews 6:59-67, 2000.

Keywords
  • Brain/anatomy & histology/embryology/growth & development
  • Embryonic and Fetal Development
  • Humans
  • Magnetic Resonance Imaging/methods
  • Magnetic Resonance Spectroscopy/methods
  • Myelin Sheath/physiology
  • Periaqueductal Gray/anatomy & histology/embryology/growth & development
  • Reference Values
Citation (ISO format)
INDER, T E, HÜPPI, Petra Susan. In vivo studies of brain development by magnetic resonance techniques. In: Mental retardation and developmental disabilities research reviews, 2000, vol. 6, n° 1, p. 59–67. doi: 10.1002/(SICI)1098-2779(2000)6:1<59::AID-MRDD8>3.0.CO;2-E
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Article (Published version)
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ISSN of the journal1080-4013
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