The role of glycopeptide antibiotics in the treatment of infective endocarditis

Gruneberg, R. N.; Antunes, F.; Chambers, H. F.; Garau, J.; Graninger, W.; Menichetti, F.; Peetermans, W. E.; Pittet, Didier; Shah, P. M.; Vogelaers, D.

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Title		The role of glycopeptide antibiotics in the treatment of infective endocarditis
Authors		Gruneberg, R. N. Antunes, F. Chambers, H. F. Garau, J. Graninger, W. Menichetti, F. Peetermans, W. E. Pittet, Didier Shah, P. M. Vogelaers, D. show all authors [1 - 10]
Published in		International Journal of Antimicrobial Agents. 1999, vol. 12, no. 3, p. 191-198
Abstract		There are several sets of guidelines for the treatment of infective endocarditis, reflecting the need for differing treatment in various countries and times. This review considers the need for differing treatment modalities and in particular the utility of the glycopeptide antibiotics vancomycin and teicoplanin. Specific recommendations are offered as to when to consider the use of glycopeptides, appropriate dosage, length of treatment course and whether to use monotherapy or combined therapy. Used judiciously, the glycopeptides give results as good as can be achieved with other antimicrobial agents without exceptional toxicity. The potential of teicoplanin for use in the outpatient treatment of infective endocarditis is considered.
Keywords		Anti-Bacterial Agents/ therapeutic use — Drug Resistance, Microbial — Endocarditis, Bacterial/ drug therapy — Glycopeptides — Humans — Practice Guidelines as Topic — Staphylococcal Infections/ drug therapy
Identifiers		PMID: 10461836
Full text		Article - Limited access to UNIGE
Structures		Faculté de médecine / Section de médecine clinique / Département de médecine interne des spécialités
Research group		Staphylocoques dorés résistants à la méthicilline et hygiène hospitalière (330)
Citation (ISO format)		GRUNEBERG, R. N. et al. The role of glycopeptide antibiotics in the treatment of infective endocarditis. In: International Journal of Antimicrobial Agents, 1999, vol. 12, n° 3, p. 191-198. https://archive-ouverte.unige.ch/unige:7284