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Title

The Tutsi genocide and transgenerational transmission of maternal stress: epigenetics and biology of the HPA axis

Authors
Rutembesa, Eugene
Mutabaruka, Jean
Mutesa, Léon
Published in World Journal of Biological Psychiatry. 2014, vol. 15, no. 4, p. 334-45
Abstract Transmission of parental post-traumatic stress disorder (PTSD) to offspring might be explained by transmission of epigenetic processes such as methylation status of the glucocorticoid receptor (GR) gene (NR3C1).
Keywords AdolescentAdultDNA Methylation/physiologyDepressive Disorder/etiologyEpigenesis, GeneticFemaleGenocideHumansHydrocortisone/bloodHypothalamo-Hypophyseal System/metabolismMaleMothersPituitary-Adrenal System/metabolismPregnancyPrenatal Exposure Delayed Effects/metabolismReceptors, Glucocorticoid/genetics/metabolismReceptors, Mineralocorticoid/genetics/metabolismSeverity of Illness IndexStress Disorders, Post-Traumatic/blood/etiology/metabolism
Identifiers
PMID: 24690014
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Structures
Research group Groupe Giacobino Ariane (génétique) (923)
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(ISO format)
PERROUD, Nader Ali et al. The Tutsi genocide and transgenerational transmission of maternal stress: epigenetics and biology of the HPA axis. In: World Journal of Biological Psychiatry, 2014, vol. 15, n° 4, p. 334-45. https://archive-ouverte.unige.ch/unige:72646

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Deposited on : 2015-05-18

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