Scientific article
English

The Tutsi genocide and transgenerational transmission of maternal stress: epigenetics and biology of the HPA axis

Published inThe world journal of biological psychiatry, vol. 15, no. 4, p. 334-345
Publication date2014
Abstract

Transmission of parental post-traumatic stress disorder (PTSD) to offspring might be explained by transmission of epigenetic processes such as methylation status of the glucocorticoid receptor (GR) gene (NR3C1).

Keywords
  • Adolescent
  • Adult
  • DNA Methylation/physiology
  • Depressive Disorder/etiology
  • Epigenesis, Genetic
  • Female
  • Genocide
  • Humans
  • Hydrocortisone/blood
  • Hypothalamo-Hypophyseal System/metabolism
  • Male
  • Mothers
  • Pituitary-Adrenal System/metabolism
  • Pregnancy
  • Prenatal Exposure Delayed Effects/metabolism
  • Receptors, Glucocorticoid/genetics/metabolism
  • Receptors, Mineralocorticoid/genetics/metabolism
  • Severity of Illness Index
  • Stress Disorders, Post-Traumatic/blood/etiology/metabolism
Citation (ISO format)
PERROUD, Nader Ali et al. The Tutsi genocide and transgenerational transmission of maternal stress: epigenetics and biology of the HPA axis. In: The world journal of biological psychiatry, 2014, vol. 15, n° 4, p. 334–345. doi: 10.3109/15622975.2013.866693
Main files (1)
Article (Published version)
accessLevelRestricted
Identifiers
Journal ISSN1562-2975
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7downloads

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