UNIGE document Scientific Article
previous document  unige:648  next document
add to browser collection

Pyoderma gangrenosum after totally implanted central venous access device insertion

Myers, Patrick-Olivier
Braun, Rolf
Hagen, Monica E.
Published in World journal of surgical oncology. 2008, vol. 6, no. 31
Abstract BACKGROUND: Pyoderma gangrenosum is an aseptic skin disease. The ulcerative form of pyoderma gangrenosum is characterized by a rapidly progressing painful irregular and undermined bordered necrotic ulcer. The aetiology of pyoderma gangrenosum remains unclear. In about 70% of cases, it is associated with a systemic disorder, most often inflammatory bowel disease, haematological disease or arthritis. In 25-50% of cases, a triggering factor such as recent surgery or trauma is identified. Treatment consists of local and systemic approaches. Systemic steroids are generally used first. If the lesions are refractory, steroids are combined with other immunosuppressive therapy or to antimicrobial agents. CASE PRESENTATION: A 90 years old patient with myelodysplastic syndrome, seeking regular transfusions required totally implanted central venous access device (Port-a-Cath(R)) insertion. Fever and inflammatory skin reaction at the site of insertion developed on the seventh post-operative day, requiring the device's explanation. A rapid progression of the skin lesions evolved into a circular skin necrosis. Intravenous steroid treatment stopped the necrosis' progression. CONCLUSION: Early diagnosis remains the most important step to the successful treatment of pyoderma gangrenosum.
Keywords Aged : 80 and overCatheterization : Central VenousCatheters : IndwellingHumansImmunosuppressive AgentsMaleMyelodysplastic SyndromesPyoderma Gangrenosum
PMID: 18325095
Full text
Article (Accepted version) (431 Kb) - public document Free access
Other version: http://www.wjso.com/content/6/1/31
Research groups Chirurgie viscérale (104)
Chirurgie viscérale (HUG)
(ISO format)
INAN, Ihsan et al. Pyoderma gangrenosum after totally implanted central venous access device insertion. In: World journal of surgical oncology, 2008, vol. 6, n° 31. doi: 10.1186/1477-7819-6-31 https://archive-ouverte.unige.ch/unige:648

661 hits



Deposited on : 2009-01-20

Export document
Format :
Citation style :