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Title

Plasma perfusion by apheresis through a Gal immunoaffinity column successfully depletes anti-Gal antibody: experience with 320 aphereses in baboons

Authors
Watts, A
Foley, A
Awwad, M
Treter, S
Oravec, G
Alwayn, I P
Kozlowski, T
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Published in Xenotransplantation. 2000, vol. 7, no. 3, p. 181-5
Abstract Anti-Galalpha1-3Gal (Gal) antibodies (Gal Ab) contribute to the rejection of porcine organs transplanted into primates. Extracorporeal immunoadsorption (EIA) has been developed to eliminate Gal Ab from the circulation.
Keywords AnimalsChromatography, AffinityDisaccharides/immunologyEnzyme-Linked Immunosorbent AssayEpitopes/immunologyExtracorporeal CirculationGraft Rejection/immunologyImmunoglobulin G/blood/isolation & purificationImmunoglobulin M/blood/isolation & purificationImmunosorbent TechniquesPapioPerfusionPlasmapheresis/methodsSwineTransplantation, Heterologous/immunology
Identifiers
PMID: 11021663
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Research group Cultures cellulaires et transplantations (519)
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WATTS, A et al. Plasma perfusion by apheresis through a Gal immunoaffinity column successfully depletes anti-Gal antibody: experience with 320 aphereses in baboons. In: Xenotransplantation, 2000, vol. 7, n° 3, p. 181-5. https://archive-ouverte.unige.ch/unige:55613

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Deposited on : 2015-04-20

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