Scientific article
English

Plasma perfusion by apheresis through a Gal immunoaffinity column successfully depletes anti-Gal antibody: experience with 320 aphereses in baboons

Published inXenotransplantation, vol. 7, no. 3, p. 181-185
Publication date2000
Abstract

Anti-Galalpha1-3Gal (Gal) antibodies (Gal Ab) contribute to the rejection of porcine organs transplanted into primates. Extracorporeal immunoadsorption (EIA) has been developed to eliminate Gal Ab from the circulation.

Keywords
  • Animals
  • Chromatography, Affinity
  • Disaccharides/immunology
  • Enzyme-Linked Immunosorbent Assay
  • Epitopes/immunology
  • Extracorporeal Circulation
  • Graft Rejection/immunology
  • Immunoglobulin G/blood/isolation & purification
  • Immunoglobulin M/blood/isolation & purification
  • Immunosorbent Techniques
  • Papio
  • Perfusion
  • Plasmapheresis/methods
  • Swine
  • Transplantation, Heterologous/immunology
Citation (ISO format)
WATTS, A et al. Plasma perfusion by apheresis through a Gal immunoaffinity column successfully depletes anti-Gal antibody: experience with 320 aphereses in baboons. In: Xenotransplantation, 2000, vol. 7, n° 3, p. 181–185. doi: 10.1034/j.1399-3089.2000.00068.x
Main files (1)
Article (Published version)
accessLevelRestricted
Identifiers
ISSN of the journal0908-665X
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Creation20/04/2015 12:31:00
First validation20/04/2015 12:31:00
Update time14/03/2023 23:11:55
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