New combined serum creatinine and cystatin C quadratic formula for GFR assessment in children

Chehade, Hassib; Cachat, François; Jannot Berthier, Anne-Sophie; Meyrat, Blaise-Julien; Mosig, Dolores; Bardy, Daniel; Parvex, Paloma Maria; Girardin, Eric

doi:10.2215/CJN.00940113

Scientific article

English

New combined serum creatinine and cystatin C quadratic formula for GFR assessment in children

ContributorsChehade, Hassib; Cachat, François; Jannot Berthier, Anne-Sophie; Meyrat, Blaise-Julien; Mosig, Dolores; Bardy, Daniel; Parvex, Paloma Maria; Girardin, Eric

Published inClinical journal of the American Society of Nephrology, vol. 9, no. 1, p. 54-63

Publication date2014

Abstract

The estimated GFR (eGFR) is important in clinical practice. To find the best formula for eGFR, this study assessed the best model of correlation between sinistrin clearance (iGFR) and the solely or combined cystatin C (CysC)- and serum creatinine (SCreat)-derived models. It also evaluated the accuracy of the combined Schwartz formula across all GFR levels.

Keywords

Adolescent
Age Factors
Biological Markers/blood
Child
Child, Preschool
Creatinine/blood
Cystatin C/blood
Female
Glomerular Filtration Rate
Humans
Kidney/physiopathology
Linear Models
Logistic Models
Male
Models, Cardiovascular
Predictive Value of Tests
Renal Insufficiency, Chronic/blood/diagnosis/physiopathology
Reproducibility of Results
Severity of Illness Index

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département de pédiatrie, gynécologie et obstétrique

Research groups

Pathogénèse du syndrome néphrotique idiopathique de l'enfant (180)

Citation (ISO format)

CHEHADE, Hassib et al. New combined serum creatinine and cystatin C quadratic formula for GFR assessment in children. In: Clinical journal of the American Society of Nephrology, 2014, vol. 9, n° 1, p. 54–63. doi: 10.2215/CJN.00940113

Article (Published version)

Identifiers

PID : unige:55190
DOI : 10.2215/CJN.00940113
PMID : 24202134

Journal ISSN1555-9041

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New combined serum creatinine and cystatin C quadratic formula for GFR assessment in children

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