Decrease of prefrontal metabolism after subthalamic stimulation in obsessive-compulsive disorder: a positron emission tomography study

Le Jeune, Florence; Vérin, Marc; Ndiaye, Karim Babacar Joseph; Drapier, Dominique; Leray, Emmanuelle; Du Montcel, Sophie Tezenas; Baup, Nicolas; Pelissolo, Antoine; Polosan, Mircea; Mallet, Luc; Yelnik, Jérome; Devaux, Bertrand; Fontaine, Denys; Chereau, Isabelle; Bourguignon, Aurélie; Peron, Julie; Sauleau, Paul; Raoul, Sylvie; Garin, Etienne; Krebs, Marie-Odile; Jaafari, Nematollah; Millet, Bruno

doi:10.1016/j.biopsych.2010.06.033

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Title		Decrease of prefrontal metabolism after subthalamic stimulation in obsessive-compulsive disorder: a positron emission tomography study
Authors		Le Jeune, Florence Vérin, Marc Ndiaye, Karim Babacar Joseph Drapier, Dominique Leray, Emmanuelle Du Montcel, Sophie Tezenas Baup, Nicolas Pelissolo, Antoine Polosan, Mircea Mallet, Luc Yelnik, Jérome Devaux, Bertrand Fontaine, Denys Chereau, Isabelle Bourguignon, Aurélie Peron, Julie Sauleau, Paul Raoul, Sylvie Garin, Etienne Krebs, Marie-Odile Jaafari, Nematollah Millet, Bruno show all authors [1 - 22]
Collaboration		French Stimulation dans le trouble obsessionnel compulsif (STOC) study group With : Pollak, Pierre
Published in		Biological Psychiatry. 2010, vol. 68, no. 11, p. 1016-22
Abstract		High-frequency bilateral subthalamic nucleus (STN) deep brain stimulation (DBS) is a promising treatment in refractory obsessive-compulsive disorder (OCD).
Keywords		Adult — Brain Mapping — Cross-Over Studies — Deep Brain Stimulation — Double-Blind Method — Female — Gyrus Cinguli/radionuclide imaging — Humans — Image Processing, Computer-Assisted — Male — Middle Aged — Obsessive-Compulsive Disorder/radionuclide imaging/therapy — Positron-Emission Tomography — Prefrontal Cortex/radionuclide imaging — Severity of Illness Index — Statistics, Nonparametric — Subthalamic Nucleus/surgery — Treatment Outcome
Identifiers		DOI: 10.1016/j.biopsych.2010.06.033 PMID: 20951978
Full text		Article (Published version) (614 Kb) - Limited access to UNIGE
Structures		Faculté de médecine / Section de médecine clinique / Département des neurosciences cliniques
Research group		Maladie de Parkinson (911)
Citation (ISO format)		LE JEUNE, Florence et al. Decrease of prefrontal metabolism after subthalamic stimulation in obsessive-compulsive disorder: a positron emission tomography study. In: Biological Psychiatry, 2010, vol. 68, n° 11, p. 1016-22. doi: 10.1016/j.biopsych.2010.06.033 https://archive-ouverte.unige.ch/unige:45245