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Title

Combined antiviral-immunosuppressive treatment in human T-lymphotrophic virus 1-Sjögren-associated myelopathy
Authors
Pot, Caroline
Chizzolini, Carlo
Vokatch-boldyreva, Natalia
Tiercy, Jean-Marie
Ribi, Camillo
Landis, Theodor
Perren, Fabienne
Published in Archives of Neurology. 2006, vol. 63, no. 9, p. 1318-20
Abstract In several studies, antiretroviral drugs (principally zidovudine) have been used with success in the treatment of myelopathy associated with human T-lymphotrophic virus 1 (HTLV-1) (tropical spastic paraparesis-HTLV-1-associated myelopathy). The retrovirus HTLV-1 has been implicated as a causative agent of Sjögren syndrome (SS) in clinical reports and murine experiments. Moreover, a recognized complication of primary SS is a myelopathy, which has been shown in case reports to respond to immunosuppressive treatment.
Keywords Adenine/analogs & derivatives/therapeutic use — Antiviral Agents/therapeutic use — Drug Therapy, Combination — Female — HTLV-I Infections/complications/drug therapy/radiotherapy — Humans — Immunosuppressive Agents/therapeutic use — Lamivudine/therapeutic use — Magnetic Resonance Imaging/methods — Methylprednisolone/therapeutic use — Middle Aged — Organophosphonates/therapeutic use — Prednisone/therapeutic use — Sjogren's Syndrome/complications/drug therapy/radiography
Identifiers
PMID: 16966512
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Article (Published version) (131 Kb) - public document Free access
Structures
Faculté de médecine / Section de médecine fondamentale / Département de pathologie et immunologie
Faculté de médecine / Section de médecine clinique / Département des neurosciences cliniques
Research group La matrice extracellulaire (651)
Citation
(ISO format) 		POT, Caroline et al. Combined antiviral-immunosuppressive treatment in human T-lymphotrophic virus 1-Sjögren-associated myelopathy. In: Archives of Neurology, 2006, vol. 63, n° 9, p. 1318-20. https://archive-ouverte.unige.ch/unige:44610

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Deposited on : 2015-01-07

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