en
Scientific article
English

Scatter characterization and correction for simultaneous multiple small-animal PET imaging

Published inMolecular imaging and biology, vol. 16, no. 2, p. 199-209
Publication date2014
Abstract

The rapid growth and usage of small-animal positron emission tomography (PET) in molecular imaging research has led to increased demand on PET scanner's time. One potential solution to increase throughput is to scan multiple rodents simultaneously. However, this is achieved at the expense of deterioration of image quality and loss of quantitative accuracy owing to enhanced effects of photon attenuation and Compton scattering. The purpose of this work is, first, to characterize the magnitude and spatial distribution of the scatter component in small-animal PET imaging when scanning single and multiple rodents simultaneously and, second, to assess the relevance and evaluate the performance of scatter correction under similar conditions.

Keywords
  • Animals
  • Computer Simulation
  • Image Enhancement
  • Mice
  • Monte Carlo Method
  • Phantoms, Imaging
  • Positron-Emission Tomography/methods
  • Rats
  • Scattering, Radiation
Citation (ISO format)
PRASAD, Rameshwar, ZAIDI, Habib. Scatter characterization and correction for simultaneous multiple small-animal PET imaging. In: Molecular imaging and biology, 2014, vol. 16, n° 2, p. 199–209. doi: 10.1007/s11307-013-0683-2
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Article (Published version)
accessLevelRestricted
Identifiers
ISSN of the journal1536-1632
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Technical informations

Creation12/19/2014 4:01:00 PM
First validation12/19/2014 4:01:00 PM
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