en
Scientific article
Open access
English

Dense representation of natural odorants in the mouse olfactory bulb

Published inNature neuroscience, vol. 15, no. 4, p. 537-539
Publication date2012
Abstract

In mammals, odorant molecules are thought to activate only a few glomeruli, leading to the hypothesis that odor representation in the olfactory bulb is sparse. However, the studies supporting this model used anesthetized animals or monomolecular odorants at limited concentration ranges. Using optical imaging and two-photon microscopy, we found that natural odorants at their native concentrations could elicit dense representations in the olfactory bulb. Both anesthesia and odorant concentration were found to modulate the representation density of natural odorants.

Keywords
  • Functional imaging
  • Olfactory bulb glomeruli
  • Sensory representation
  • Intrinsic signals
  • Awake mice
Funding
  • Swiss National Science Foundation - PP0033_119169, PP00P3_139189
  • European Commission - From neurons to behavior: analysis of the mechanisms underlying sensory coding and plasticity in chemical senses [243344]
Citation (ISO format)
VINCIS, Roberto et al. Dense representation of natural odorants in the mouse olfactory bulb. In: Nature neuroscience, 2012, vol. 15, n° 4, p. 537–539. doi: 10.1038/nn.3057
Main files (1)
Article (Accepted version)
accessLevelPublic
Identifiers
ISSN of the journal1097-6256
563views
246downloads

Technical informations

Creation09/29/2014 12:49:00 PM
First validation09/29/2014 12:49:00 PM
Update time03/14/2023 9:51:00 PM
Status update03/14/2023 9:51:00 PM
Last indexation01/16/2024 12:04:57 PM
All rights reserved by Archive ouverte UNIGE and the University of GenevaunigeBlack