Scientific article
Open access

Dense representation of natural odorants in the mouse olfactory bulb

Published inNature neuroscience, vol. 15, no. 4, p. 537-539
Publication date2012

In mammals, odorant molecules are thought to activate only a few glomeruli, leading to the hypothesis that odor representation in the olfactory bulb is sparse. However, the studies supporting this model used anesthetized animals or monomolecular odorants at limited concentration ranges. Using optical imaging and two-photon microscopy, we found that natural odorants at their native concentrations could elicit dense representations in the olfactory bulb. Both anesthesia and odorant concentration were found to modulate the representation density of natural odorants.

  • Functional imaging
  • Olfactory bulb glomeruli
  • Sensory representation
  • Intrinsic signals
  • Awake mice
  • Swiss National Science Foundation - PP0033_119169, PP00P3_139189
  • European Commission - From neurons to behavior: analysis of the mechanisms underlying sensory coding and plasticity in chemical senses [243344]
Citation (ISO format)
VINCIS, Roberto et al. Dense representation of natural odorants in the mouse olfactory bulb. In: Nature neuroscience, 2012, vol. 15, n° 4, p. 537–539. doi: 10.1038/nn.3057
Main files (1)
Article (Accepted version)
ISSN of the journal1097-6256

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