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Title

Dense representation of natural odorants in the mouse olfactory bulb

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Published in Nature Neuroscience. 2012, vol. 15, no. 4, p. 537-539
Abstract In mammals, odorant molecules are thought to activate only a few glomeruli, leading to the hypothesis that odor representation in the olfactory bulb is sparse. However, the studies supporting this model used anesthetized animals or monomolecular odorants at limited concentration ranges. Using optical imaging and two-photon microscopy, we found that natural odorants at their native concentrations could elicit dense representations in the olfactory bulb. Both anesthesia and odorant concentration were found to modulate the representation density of natural odorants.
Keywords Functional imagingOlfactory bulb glomeruliSensory representationIntrinsic signalsAwake mice
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PMID: 22406552
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Research group Groupe Carleton Alan (neurosciences fondamentales) (876)
Projects FNS: PP0033_119169, PP00P3_139189
FP7: NEUROCHEMS
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VINCIS, Roberto et al. Dense representation of natural odorants in the mouse olfactory bulb. In: Nature Neuroscience, 2012, vol. 15, n° 4, p. 537-539. https://archive-ouverte.unige.ch/unige:40887

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Deposited on : 2014-10-15

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