en
Scientific article
Review
Open access
English

Role of the parasite and host cytoskeleton in apicomplexa parasitism

Published inCell host & microbe, vol. 5, no. 6, p. 602-611
Publication date2009
Abstract

The phylum Apicomplexa includes a large and diverse group of obligate intracellular parasites that rely on actomyosin-based motility to migrate, enter host cells, and egress from infected cells. To ensure their intracellular survival and replication, the apicomplexans have evolved sophisticated strategies for subversion of the host cytoskeleton. Given the properties in common between the host and parasite cytoskeleton, dissecting their individual contribution to the establishment of parasitic infection has been challenging. Nevertheless, recent studies have provided new insights into the mechanisms by which parasites subvert the dynamic properties of host actin and tubulin to promote their entry, development, and egress.

Keywords
  • Actins/metabolism
  • Animals
  • Apicomplexa/physiology
  • Cytoskeleton/metabolism
  • Host-Parasite Interactions
  • Models, Biological
  • Tubulin/metabolism
Citation (ISO format)
FRENAL, Karine, SOLDATI-FAVRE, Dominique. Role of the parasite and host cytoskeleton in apicomplexa parasitism. In: Cell host & microbe, 2009, vol. 5, n° 6, p. 602–611. doi: 10.1016/j.chom.2009.05.013
Main files (1)
Article (Accepted version)
accessLevelPublic
Identifiers
ISSN of the journal1931-3128
660views
530downloads

Technical informations

Creation11/05/2009 10:20:00 AM
First validation11/05/2009 10:20:00 AM
Update time03/14/2023 3:17:10 PM
Status update03/14/2023 3:17:10 PM
Last indexation05/02/2024 11:22:41 AM
All rights reserved by Archive ouverte UNIGE and the University of GenevaunigeBlack