Scientific article
Open access

Role of the parasite and host cytoskeleton in apicomplexa parasitism

Published inCell host & microbe, vol. 5, no. 6, p. 602-611
Publication date2009

The phylum Apicomplexa includes a large and diverse group of obligate intracellular parasites that rely on actomyosin-based motility to migrate, enter host cells, and egress from infected cells. To ensure their intracellular survival and replication, the apicomplexans have evolved sophisticated strategies for subversion of the host cytoskeleton. Given the properties in common between the host and parasite cytoskeleton, dissecting their individual contribution to the establishment of parasitic infection has been challenging. Nevertheless, recent studies have provided new insights into the mechanisms by which parasites subvert the dynamic properties of host actin and tubulin to promote their entry, development, and egress.

  • Actins/metabolism
  • Animals
  • Apicomplexa/physiology
  • Cytoskeleton/metabolism
  • Host-Parasite Interactions
  • Models, Biological
  • Tubulin/metabolism
Citation (ISO format)
FRENAL, Karine, SOLDATI-FAVRE, Dominique. Role of the parasite and host cytoskeleton in apicomplexa parasitism. In: Cell host & microbe, 2009, vol. 5, n° 6, p. 602–611. doi: 10.1016/j.chom.2009.05.013
Main files (1)
Article (Accepted version)
ISSN of the journal1931-3128

Technical informations

Creation11/05/2009 10:20:00 AM
First validation11/05/2009 10:20:00 AM
Update time03/14/2023 3:17:10 PM
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