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English

Role of the parasite and host cytoskeleton in apicomplexa parasitism

Contributors

Frenal, Karine; Soldati-Favre, Dominique

Published in

Cell host & microbe, vol. 5, no. 6, p. 602-611

Publication date

2009

Abstract

The phylum Apicomplexa includes a large and diverse group of obligate intracellular parasites that rely on actomyosin-based motility to migrate, enter host cells, and egress from infected cells. To ensure their intracellular survival and replication, the apicomplexans have evolved sophisticated strategies for subversion of the host cytoskeleton. Given the properties in common between the host and parasite cytoskeleton, dissecting their individual contribution to the establishment of parasitic infection has been challenging. Nevertheless, recent studies have provided new insights into the mechanisms by which parasites subvert the dynamic properties of host actin and tubulin to promote their entry, development, and egress.

Keywords

  • Actins/metabolism
  • Animals
  • Apicomplexa/physiology
  • Cytoskeleton/metabolism
  • Host-Parasite Interactions
  • Models, Biological
  • Tubulin/metabolism

UNIGE affiliation entities

UNIGE research groups

Citation (ISO format)

FRENAL, Karine, SOLDATI-FAVRE, Dominique. Role of the parasite and host cytoskeleton in apicomplexa parasitism. In: Cell host & microbe, 2009, vol. 5, n° 6, p. 602–611. doi: 10.1016/j.chom.2009.05.013

Main files (1)

Article (Accepted version)

Identifiers

Journal ISSN

1931-3128
764views
717downloads

Technical informations

Creation

05/11/2009 10:20:00

First validation

05/11/2009 10:20:00

Update

14/03/2023 15:17:10

Status update

14/03/2023 15:17:10

Last indexation

29/10/2024 12:30:56
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