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Mechanism of disorientation: reality filtering versus content monitoring

Published in Cortex. 2013, vol. 49, no. 10, p. 2628-36
Abstract Disorientation is frequent after brain damage. It is a constituent component of post-traumatic amnesia and was part of the original definition of the Korsakoff syndrome, together with amnesia and confabulations. Orbitofrontal reality filtering is a pre-conscious memory control process that has been held accountable for disorientation and a specific type of confabulations that patients act upon. A recent study questioned the specificity of this process and suggested that confabulating patients who failed in orbitofrontal reality filtering similarly failed to monitor the precise content of memories, a critical step within the strategic retrieval account, which describes a series of processes leading up to the recollection of memories. In the present study we combined the proposed experimental requirements of both processes in a single continuous recognition task and tested a group of 21 patients with a matched deficit of delayed free recall. We found that only deficient reality filtering, but not content monitoring, significantly correlated with disorientation and distinguished between confabulators and non-confabulators. Thus, reality confusion, as evident in disorientation and behaviourally spontaneous confabulation, primarily reflects an inability to monitor memories' relation with ongoing reality rather than to monitor their precise content.
Keywords AdultAgedAmnesia/psychologyConfusion/psychologyData Interpretation, StatisticalFemaleHumansLearningMaleMemory/physiologyMental Recall/physiologyMiddle AgedNeuropsychological TestsOrientation/physiologyPerception/physiologyPsychomotor Performance/physiologyTrail Making TestVerbal Behavior
PMID: 24012137
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Research groups Lésions cérébrales et attention spatiale (705)
Amnésie (289)
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BOUZERDA-WAHLEN, Aurélie et al. Mechanism of disorientation: reality filtering versus content monitoring. In: Cortex, 2013, vol. 49, n° 10, p. 2628-36. https://archive-ouverte.unige.ch/unige:39271

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Deposited on : 2014-08-07

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