We present the results of a search in pp¯ collisions at s√=1.8TeV for anomalous production of events containing a photon with large transverse energy and a lepton (e or μ) with large transverse energy, using 86 pb-1 of data collected with the Collider Detector at Fermilab during the 1994–1995 collider run at the Fermilab Tevatron. The presence of large missing transverse energy (ET), additional photons, or additional leptons in these events is also analyzed. The results are consistent with standard model expectations, with the possible exception of photon-lepton events with large ET, for which the observed total is 16 events and the expected mean total is 7.6±0.7 events.