Article (Published version) (65 Kb) - Free access
Are criteria for islet and pancreas donors sufficiently different to minimize competition?
|Published in||American Journal of Transplantation. 2004, vol. 4, no. 5, p. 763-6|
|Abstract||Islet and pancreas transplantation may compete for a limited number of organs. We analyzed records from the national Swiss transplant registry during a 4-year period to investigate the proportion of donors that are suitable for islet and pancreas transplantation. Suitability for pancreas transplantation was mainly defined as: age 10-45 years; weight <or= 80 kg; BMI <or= 25 kg/m(2); amylasemia <or= 150 U/l; ICU stay <or= 3 days and absence of severe hypotension (MAP <or= 60 mmHG). Between 1.1.1997 and 31.12.2000, data of 407 donors were collected, from which 321 donors were included in the study. Thirty-three (10%), 143 (45%), and 23 (7%) donors fulfilled the criteria for pancreas, islet transplantation, and both procedures, respectively. Giving priority to pancreas transplantation and accepting the absence of one selection criterion, 90 (28%) pancreas and 100 (31%) islet donors were identified. We conclude that with current allocation policies prioritizing pancreas transplantation, pancreas and islet transplantation may coexist with little competition.|
|Keywords||Adult — Aged — Child — Humans — Islets of Langerhans Transplantation — Middle Aged — Pancreas Transplantation — Patient Selection — Tissue Donors/supply & distribution — Tissue and Organ Procurement/standards|
|Research groups||Chirurgie viscérale (104)|
Hépatologie chirurgicale (327)
|RIS, Frédéric et al. Are criteria for islet and pancreas donors sufficiently different to minimize competition?. In: American Journal of Transplantation, 2004, vol. 4, n° 5, p. 763-6. https://archive-ouverte.unige.ch/unige:37178|