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Are criteria for islet and pancreas donors sufficiently different to minimize competition?

Published in American journal of transplantation. 2004, vol. 4, no. 5, p. 763-6
Abstract Islet and pancreas transplantation may compete for a limited number of organs. We analyzed records from the national Swiss transplant registry during a 4-year period to investigate the proportion of donors that are suitable for islet and pancreas transplantation. Suitability for pancreas transplantation was mainly defined as: age 10-45 years; weight <or= 80 kg; BMI <or= 25 kg/m(2); amylasemia <or= 150 U/l; ICU stay <or= 3 days and absence of severe hypotension (MAP <or= 60 mmHG). Between 1.1.1997 and 31.12.2000, data of 407 donors were collected, from which 321 donors were included in the study. Thirty-three (10%), 143 (45%), and 23 (7%) donors fulfilled the criteria for pancreas, islet transplantation, and both procedures, respectively. Giving priority to pancreas transplantation and accepting the absence of one selection criterion, 90 (28%) pancreas and 100 (31%) islet donors were identified. We conclude that with current allocation policies prioritizing pancreas transplantation, pancreas and islet transplantation may coexist with little competition.
Keywords AdultAgedChildHumansIslets of Langerhans TransplantationMiddle AgedPancreas TransplantationPatient SelectionTissue Donors/supply & distributionTissue and Organ Procurement/standards
PMID: 15084172
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Research groups Chirurgie viscérale (104)
Chirurgie viscérale (HUG)
Hépatologie chirurgicale (327)
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RIS, Frédéric et al. Are criteria for islet and pancreas donors sufficiently different to minimize competition?. In: American Journal of Transplantation, 2004, vol. 4, n° 5, p. 763-6. doi: 10.1111/j.1600-6143.2004.00409.x https://archive-ouverte.unige.ch/unige:37178

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Deposited on : 2014-06-04

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