Are criteria for islet and pancreas donors sufficiently different to minimize competition?

Ris, Frédéric; Toso, Christian; Unno Veith, Florence; Majno, Pietro; Morel, Philippe; Oberholzer, José

doi:10.1111/j.1600-6143.2004.00409.x

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Title		Are criteria for islet and pancreas donors sufficiently different to minimize competition?
Authors		Ris, Frédéric Toso, Christian Unno Veith, Florence Majno, Pietro Morel, Philippe Oberholzer, José
Published in		American Journal of Transplantation. 2004, vol. 4, no. 5, p. 763-6
Abstract		Islet and pancreas transplantation may compete for a limited number of organs. We analyzed records from the national Swiss transplant registry during a 4-year period to investigate the proportion of donors that are suitable for islet and pancreas transplantation. Suitability for pancreas transplantation was mainly defined as: age 10-45 years; weight <or= 80 kg; BMI <or= 25 kg/m(2); amylasemia <or= 150 U/l; ICU stay <or= 3 days and absence of severe hypotension (MAP <or= 60 mmHG). Between 1.1.1997 and 31.12.2000, data of 407 donors were collected, from which 321 donors were included in the study. Thirty-three (10%), 143 (45%), and 23 (7%) donors fulfilled the criteria for pancreas, islet transplantation, and both procedures, respectively. Giving priority to pancreas transplantation and accepting the absence of one selection criterion, 90 (28%) pancreas and 100 (31%) islet donors were identified. We conclude that with current allocation policies prioritizing pancreas transplantation, pancreas and islet transplantation may coexist with little competition.
Keywords		Adult — Aged — Child — Humans — Islets of Langerhans Transplantation — Middle Aged — Pancreas Transplantation — Patient Selection — Tissue Donors/supply & distribution — Tissue and Organ Procurement/standards
Identifiers		DOI: 10.1111/j.1600-6143.2004.00409.x PMID: 15084172
Full text		Article (Published version) (65 Kb) - Free access
Structures		Faculté de médecine / Section de médecine clinique / Département de chirurgie
Research groups		Chirurgie viscérale (104) Hépatologie chirurgicale (327)
Citation (ISO format)		RIS, Frédéric et al. Are criteria for islet and pancreas donors sufficiently different to minimize competition?. In: American Journal of Transplantation, 2004, vol. 4, n° 5, p. 763-6. doi: 10.1111/j.1600-6143.2004.00409.x https://archive-ouverte.unige.ch/unige:37178