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Title

Vesicular Structures Self-Assembled from Oligonucleotide-Polymer Hybrids: Mechanical Prevention of Bacterial Colonization Upon their Surface Tethering Through Hybridization

Authors
Cottenye, Nicolas
Anselme, Karine
Ploux, Lydie
Published in Advanced Functional Materials. 2012, vol. 22, no. 23, p. 4891-4898
Abstract In order to design soft coatings, surface tethering of vesicular structures self-assembled from oligonucleotide-polymer hybrids is achieved through hybridization. Watson-Crick base-pairing occurs between the nucleotide sequences involved in the self-assembly and their surface-tethered complementary sequences. Combining the quartz crystal microbalance and in situ observations using confocal laser scanning microscopy, it is evidenced that the vesicles retain their morphology even under fl ow stress. Surprisingly, these soft surfaces prevent bacterial colonization.
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Other version: http://doi.wiley.com/10.1002/adfm.201200988
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COTTENYE, Nicolas et al. Vesicular Structures Self-Assembled from Oligonucleotide-Polymer Hybrids: Mechanical Prevention of Bacterial Colonization Upon their Surface Tethering Through Hybridization. In: Advanced Functional Materials, 2012, vol. 22, n° 23, p. 4891-4898. https://archive-ouverte.unige.ch/unige:34033

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Deposited on : 2014-02-03

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