The effect of breathing irregularities on quantitative accuracy of respiratory gated PET∕CT

Teo, Boon-Keng; Saboury, Babak; Munbodh, Reshma; Scheuermann, Joshua; Torigian, Drew A; Zaidi, Habib; Alavi, Abass

doi:10.1118/1.4766876

Scientific article

Open access

English

The effect of breathing irregularities on quantitative accuracy of respiratory gated PET∕CT

ContributorsTeo, Boon-Keng; Saboury, Babak; Munbodh, Reshma; Scheuermann, Joshua; Torigian, Drew A; Zaidi, Habib

; Alavi, Abass

Published inMedical physics, vol. 39, no. 12, p. 7390-7397

Publication date2012

Abstract

4D positron emission tomography and computed tomography (PET∕CT) can be used to reduce motion artifacts by correlating the raw PET data with the respiratory cycle. The accuracy of each PET phase is dependent on the reproducibility and consistency of the breathing cycle during acquisition. The objective of this study is to evaluate the impact of breathing amplitude and phase irregularities on the quantitative accuracy of 4D PET standardized uptake value (SUV) measurements. In addition, the magnitude of quantitative errors due to respiratory motion and partial volume error are compared.

Keywords

Artifacts
Four-Dimensional Computed Tomography/instrumentation/methods
Image Enhancement/methods
Image Interpretation, Computer-Assisted/methods
Motion
Phantoms, Imaging
Positron-Emission Tomography and Computed Tomography/instrumentation/methods
Reproducibility of Results
Respiratory Mechanics
Respiratory-Gated Imaging Techniques/instrumentation/methods
Sensitivity and Specificity

Affiliation

Faculté de médecine / Section de médecine clinique / Département de radiologie et informatique médicale

Research group

Imagerie Médicale (TEP et TEMP) (542)

Funding

Swiss National Science Foundation - SNF 31003A-135576

Citation (ISO format)

TEO, Boon-Keng et al. The effect of breathing irregularities on quantitative accuracy of respiratory gated PET∕CT. In: Medical physics, 2012, vol. 39, n° 12, p. 7390–7397. doi: 10.1118/1.4766876

Article (Published version)

Identifiers

PID : unige:32011
DOI : 10.1118/1.4766876
PMID : 23231288

ISSN of the journal0094-2405

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The effect of breathing irregularities on quantitative accuracy of respiratory gated PET∕CT

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