Selective acquired long QT syndrome (saLQTS) upon risperidone treatment

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Title		Selective acquired long QT syndrome (saLQTS) upon risperidone treatment
Authors		Lazarczyk, Maciej Jakub Bhuiyan, Zahir A Perrin, Nicolas Giannakopoulos, Panteleimon
Published in		BMC psychiatry. 2012, vol. 12, 220
Abstract		Numerous structurally unrelated drugs, including antipsychotics, can prolong QT interval and trigger the acquired long QT syndrome (aLQTS). All of them are thought to act at the level of KCNH2, a subunit of the potassium channel. Although the QT-prolonging drugs are proscribed in the subjects with aLQTS, the individual response to diverse QT-prolonging drugs may vary substantially.
Keywords		Adult — Antipsychotic Agents/adverse effects — Clozapine/adverse effects — Electrocardiography — Female — Humans — Long QT Syndrome/etiology — Potassium Channels/drug effects/genetics — Risperidone/adverse effects — Schizophrenia/drug therapy/genetics
Identifiers		DOI: 10.1186/1471-244X-12-220 PMID: 23216910
Full text		Article (Published version) (312 Kb) - Free access
Structures		Faculté de médecine / Section de médecine clinique / Département de psychiatrie
Research group		Groupe Giannakopoulos Panteleimon (psychiatrie générale) (201)
Citation (ISO format)		LAZARCZYK, Maciej Jakub et al. Selective acquired long QT syndrome (saLQTS) upon risperidone treatment. In: BMC psychiatry, 2012, vol. 12, p. 220. doi: 10.1186/1471-244X-12-220 https://archive-ouverte.unige.ch/unige:31978

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Deposited on : 2013-12-10

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