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Scientific article
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English

Selective acquired long QT syndrome (saLQTS) upon risperidone treatment

Published inBMC psychiatry, vol. 12, 220
Publication date2012
Abstract

Numerous structurally unrelated drugs, including antipsychotics, can prolong QT interval and trigger the acquired long QT syndrome (aLQTS). All of them are thought to act at the level of KCNH2, a subunit of the potassium channel. Although the QT-prolonging drugs are proscribed in the subjects with aLQTS, the individual response to diverse QT-prolonging drugs may vary substantially.

Keywords
  • Adult
  • Antipsychotic Agents/adverse effects
  • Clozapine/adverse effects
  • Electrocardiography
  • Female
  • Humans
  • Long QT Syndrome/etiology
  • Potassium Channels/drug effects/genetics
  • Risperidone/adverse effects
  • Schizophrenia/drug therapy/genetics
Citation (ISO format)
LAZARCZYK, Maciej Jakub et al. Selective acquired long QT syndrome (saLQTS) upon risperidone treatment. In: BMC psychiatry, 2012, vol. 12, p. 220. doi: 10.1186/1471-244X-12-220
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Article (Published version)
Identifiers
ISSN of the journal1471-244X
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229downloads

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Creation12/09/2013 8:01:00 PM
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