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Title

Selective acquired long QT syndrome (saLQTS) upon risperidone treatment
Authors
Lazarczyk, Maciej Jakub
Bhuiyan, Zahir A
Perrin, Nicolas
Giannakopoulos, Panteleimon
Published in BMC Psychiatry. 2012, vol. 12, p. 220
Abstract Numerous structurally unrelated drugs, including antipsychotics, can prolong QT interval and trigger the acquired long QT syndrome (aLQTS). All of them are thought to act at the level of KCNH2, a subunit of the potassium channel. Although the QT-prolonging drugs are proscribed in the subjects with aLQTS, the individual response to diverse QT-prolonging drugs may vary substantially.
Keywords Adult — Antipsychotic Agents/adverse effects — Clozapine/adverse effects — Electrocardiography — Female — Humans — Long QT Syndrome/etiology — Potassium Channels/drug effects/genetics — Risperidone/adverse effects — Schizophrenia/drug therapy/genetics
Identifiers
PMID: 23216910
Full text
Article (Published version) (312 Kb) - public document Free access
Structures
Faculté de médecine / Section de médecine clinique / Département de psychiatrie
Research group Groupe Giannakopoulos Panteleimon (psychiatrie générale) (201)
Citation
(ISO format) 		LAZARCZYK, Maciej Jakub et al. Selective acquired long QT syndrome (saLQTS) upon risperidone treatment. In: BMC Psychiatry, 2012, vol. 12, p. 220. doi: 10.1186/1471-244X-12-220 https://archive-ouverte.unige.ch/unige:31978

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Deposited on : 2013-12-10

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