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Selective acquired long QT syndrome (saLQTS) upon risperidone treatment |
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Published in | BMC psychiatry. 2012, vol. 12, 220 | |
Abstract | Numerous structurally unrelated drugs, including antipsychotics, can prolong QT interval and trigger the acquired long QT syndrome (aLQTS). All of them are thought to act at the level of KCNH2, a subunit of the potassium channel. Although the QT-prolonging drugs are proscribed in the subjects with aLQTS, the individual response to diverse QT-prolonging drugs may vary substantially. | |
Keywords | Adult — Antipsychotic Agents/adverse effects — Clozapine/adverse effects — Electrocardiography — Female — Humans — Long QT Syndrome/etiology — Potassium Channels/drug effects/genetics — Risperidone/adverse effects — Schizophrenia/drug therapy/genetics | |
Identifiers | PMID: 23216910 | |
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Research group | Groupe Giannakopoulos Panteleimon (psychiatrie générale) (201) | |
Citation (ISO format) | LAZARCZYK, Maciej Jakub et al. Selective acquired long QT syndrome (saLQTS) upon risperidone treatment. In: BMC psychiatry, 2012, vol. 12, p. 220. doi: 10.1186/1471-244X-12-220 https://archive-ouverte.unige.ch/unige:31978 |