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Title

Selective acquired long QT syndrome (saLQTS) upon risperidone treatment

Authors
Lazarczyk, Maciej Jakub
Bhuiyan, Zahir A
Published in BMC Psychiatry. 2012, vol. 12, p. 220
Abstract Numerous structurally unrelated drugs, including antipsychotics, can prolong QT interval and trigger the acquired long QT syndrome (aLQTS). All of them are thought to act at the level of KCNH2, a subunit of the potassium channel. Although the QT-prolonging drugs are proscribed in the subjects with aLQTS, the individual response to diverse QT-prolonging drugs may vary substantially.
Keywords AdultAntipsychotic Agents/adverse effectsClozapine/adverse effectsElectrocardiographyFemaleHumansLong QT Syndrome/etiologyPotassium Channels/drug effects/geneticsRisperidone/adverse effectsSchizophrenia/drug therapy/genetics
Identifiers
PMID: 23216910
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Article (Published version) (312 Kb) - public document Free access
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Research group Groupe Giannakopoulos Panteleimon (psychiatrie générale) (201)
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LAZARCZYK, Maciej Jakub et al. Selective acquired long QT syndrome (saLQTS) upon risperidone treatment. In: BMC Psychiatry, 2012, vol. 12, p. 220. https://archive-ouverte.unige.ch/unige:31978

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Deposited on : 2013-12-10

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