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Title

Effect of perioperative systemic α2 agonists on postoperative morphine consumption and pain intensity: systematic review and meta-analysis of randomized controlled trials

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Published in Anesthesiology. 2012, vol. 116, no. 6, p. 1312-22
Abstract Systemic α2 agonists are believed to reduce pain and opioid requirements after surgery, thus decreasing the incidence of opioid-related adverse effects, including hyperalgesia.
Keywords Adrenergic alpha-2 Receptor Agonists/therapeutic useAnalgesics, Opioid/administration & dosage/adverse effects/therapeutic useAnesthesia Recovery PeriodClonidine/therapeutic useDexmedetomidine/pharmacologyHemodynamics/drug effectsHumansHyperalgesia/chemically induced/prevention & controlHypotension/chemically induced/epidemiologyMorphine/administration & dosage/adverse effects/therapeutic usePain Measurement/drug effectsPain, Postoperative/drug therapy/psychologyPostoperative Nausea and Vomiting/drug therapy/epidemiologyRandomized Controlled Trials as Topic
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PMID: 22546966
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Article (Published version) (836 Kb) - public document Free access
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Research group La Médecine Périopératoire et l'anesthésie (70)
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BLAUDSZUN, Gregoire et al. Effect of perioperative systemic α2 agonists on postoperative morphine consumption and pain intensity: systematic review and meta-analysis of randomized controlled trials. In: Anesthesiology, 2012, vol. 116, n° 6, p. 1312-22. https://archive-ouverte.unige.ch/unige:31966

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Deposited on : 2013-12-10

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