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Title

Effect of perioperative systemic α2 agonists on postoperative morphine consumption and pain intensity: systematic review and meta-analysis of randomized controlled trials
Authors
Blaudszun, Grégoire
Lysakowski, Christopher
Elia, Nadia
Tramer, Martin
Published in Anesthesiology. 2012, vol. 116, no. 6, p. 1312-22
Abstract Systemic α2 agonists are believed to reduce pain and opioid requirements after surgery, thus decreasing the incidence of opioid-related adverse effects, including hyperalgesia.
Keywords Adrenergic alpha-2 Receptor Agonists/therapeutic use — Analgesics, Opioid/administration & dosage/adverse effects/therapeutic use — Anesthesia Recovery Period — Clonidine/therapeutic use — Dexmedetomidine/pharmacology — Hemodynamics/drug effects — Humans — Hyperalgesia/chemically induced/prevention & control — Hypotension/chemically induced/epidemiology — Morphine/administration & dosage/adverse effects/therapeutic use — Pain Measurement/drug effects — Pain, Postoperative/drug therapy/psychology — Postoperative Nausea and Vomiting/drug therapy/epidemiology — Randomized Controlled Trials as Topic
Identifiers
PMID: 22546966
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Article (Published version) (836 Kb) - public document Free access
Structures
Faculté de médecine / Section de médecine clinique / Département d'anesthésiologie, pharmacologie et soins intensifs
Research group La Médecine Périopératoire et l'anesthésie (70)
Citation
(ISO format) 		BLAUDSZUN, Grégoire et al. Effect of perioperative systemic α2 agonists on postoperative morphine consumption and pain intensity: systematic review and meta-analysis of randomized controlled trials. In: Anesthesiology, 2012, vol. 116, n° 6, p. 1312-22. https://archive-ouverte.unige.ch/unige:31966

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Deposited on : 2013-12-10

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