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Effect of perioperative systemic α2 agonists on postoperative morphine consumption and pain intensity: systematic review and meta-analysis of randomized controlled trials |
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Published in | Anesthesiology. 2012, vol. 116, no. 6, p. 1312-22 | |
Abstract | Systemic α2 agonists are believed to reduce pain and opioid requirements after surgery, thus decreasing the incidence of opioid-related adverse effects, including hyperalgesia. | |
Keywords | Adrenergic alpha-2 Receptor Agonists/therapeutic use — Analgesics, Opioid/administration & dosage/adverse effects/therapeutic use — Anesthesia Recovery Period — Clonidine/therapeutic use — Dexmedetomidine/pharmacology — Hemodynamics/drug effects — Humans — Hyperalgesia/chemically induced/prevention & control — Hypotension/chemically induced/epidemiology — Morphine/administration & dosage/adverse effects/therapeutic use — Pain Measurement/drug effects — Pain, Postoperative/drug therapy/psychology — Postoperative Nausea and Vomiting/drug therapy/epidemiology — Randomized Controlled Trials as Topic | |
Identifiers | PMID: 22546966 | |
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Research group | La Médecine Périopératoire et l'anesthésie (70) | |
Citation (ISO format) | BLAUDSZUN, Grégoire et al. Effect of perioperative systemic α2 agonists on postoperative morphine consumption and pain intensity: systematic review and meta-analysis of randomized controlled trials. In: Anesthesiology, 2012, vol. 116, n° 6, p. 1312-22. doi: 10.1097/ALN.0b013e31825681cb https://archive-ouverte.unige.ch/unige:31966 |