Scientific article
Open access

Preferred antiretroviral drugs for the next decade of scale up

Published inJournal of the International AIDS Society, vol. 15, no. 2, 17986
Publication date2012

Global commitments aim to provide antiretroviral therapy (ART) to 15 million people living with HIV by 2015, and recent studies have demonstrated the potential for widespread ART to prevent HIV transmission. Increasingly, countries are adapting their national guidelines to start ART earlier, for both clinical and preventive benefits. To maximize the benefits of ART in resource-limited settings, six key principles need to guide ART choice: simplicity, tolerability and safety, durability, universal applicability, affordability and heat stability. Currently available drugs, combined with those in late-stage clinical development, hold great promise to simplify treatment in the short term. Over the longer-term, newer technologies, such as long-acting formulations and nanotechnology, could radically alter the treatment paradigm. This commentary reviews recommendations made in an expert consultation on treatment scale up in resource-limited settings.

  • Anti-Retroviral Agents/administration & dosage
  • Antiretroviral Therapy, Highly Active/methods
  • Guidelines as Topic
  • HIV Infections/drug therapy/prevention & control
  • Humans
Research group
Citation (ISO format)
ANDRIEUX-MEYER, Isabelle et al. Preferred antiretroviral drugs for the next decade of scale up. In: Journal of the International AIDS Society, 2012, vol. 15, n° 2, p. 17986. doi: 10.7448/IAS.15.2.17986
Main files (1)
Article (Published version)
ISSN of the journal1758-2652

Technical informations

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