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Title

Do brain T2/FLAIR white matter hyperintensities correspond to myelin loss in normal aging? A radiologic-neuropathologic correlation study

Authors
Tomm, AM
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Published in Acta Neuropathologica Communications. 2013, vol. 1, no. 1, p. 14
Abstract White matter hyperintensities (WMH) lesions on T2/FLAIR brain MRI are frequently seen in healthy elderly people. Whether these radiological lesions correspond to irreversible histological changes is still a matter of debate. We report the radiologic-histopathologic concordance between T2/FLAIR WMHs and neuropathologically confirmed demyelination in the periventricular, perivascular and deep white matter (WM) areas.
Identifiers
PMID: 24252608
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Research groups Démence du sujet âgé, troubles cognitifs, la symptomatologie cognitive (577)
Ischémie cérébrale et connectivité (801)
Groupe Giannakopoulos Panteleimon (psychiatrie générale) (201)
Médecine et soins palliatifs (709)
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HALLER, Sven et al. Do brain T2/FLAIR white matter hyperintensities correspond to myelin loss in normal aging? A radiologic-neuropathologic correlation study. In: Acta Neuropathologica Communications, 2013, vol. 1, n° 1, p. 14. https://archive-ouverte.unige.ch/unige:31357

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Deposited on : 2013-11-26

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