Neutralization of macrophage migration inhibitory factor (MIF) by fully human antibodies correlates with their specificity for the beta-sheet structure of MIF
ContributorsKerschbaumer, Randolf J.; Rieger, Manfred; Volkel, Dirk; Le Roy, Didier; Roger, Thierry; Garbaraviciene, Jurate; Boehncke, Wolf-Henning; Mullberg, Jurgen; Hoet, Rene M.; Wood, Clive R.; Antoine, Gerhard; Thiele, Michael; Savidis-Dacho, Helga; Dockal, Michael; Ehrlich, Hartmut; Calandra, Thierry; Scheiflinger, Friedrich
Published inThe Journal of biological chemistry, vol. 287, no. 10, p. 7446-7455
Publication date2012
Abstract
Keywords
- Amino Acid Motifs
- Animals
- Antibodies, Monoclonal/*chemistry/immunology/therapeutic use
- Antibodies, Neutralizing/*chemistry/immunology/therapeutic use
- Dermatitis, Contact/drug therapy/immunology
- Disease Models, Animal
- Humans
- Intramolecular Oxidoreductases/*chemistry/immunology
- Macrophage Migration-Inhibitory Factors/*chemistry/immunology
- Mice
- Sepsis/drug therapy/immunology
Affiliation entities Not a UNIGE publication
Citation (ISO format)
KERSCHBAUMER, Randolf J. et al. Neutralization of macrophage migration inhibitory factor (MIF) by fully human antibodies correlates with their specificity for the beta-sheet structure of MIF. In: The Journal of biological chemistry, 2012, vol. 287, n° 10, p. 7446–7455. doi: 10.1074/jbc.M111.329664
Main files (1)
Article
Identifiers
- PID : unige:29840
- DOI : 10.1074/jbc.M111.329664
- PMID : 22238348
Additional URL for this publicationhttp://www.jbc.org/content/287/10/7446.full.pdf
Journal ISSN0021-9258