UNIGE document Scientific Article
previous document  unige:2798  next document
add to browser collection
Title

A QSAR study confirming the heterogeneity of the HEPT derivatives series regarding their interaction with HIV reverse transcriptase

Authors
Tronchet, Jean M.J.
Grigorov, Martin G.
Dolatshahi-Missaghieh, Naz
Moriaud, Fabrice
Published in European Journal of Medicinal Chemistry. 1997, vol. 32, no. 4, p. 279-299
Abstract QSAR concerning the anti-HIV and cytotoxic activities of a series of HEPT analogues has been established using a Hansch-type approach (TSAR™), a neural network approach (TSAR) and a pharmacophore search method (CATALYST™). The techniques employed allowed reliable activity predictions and confirmed the heterogeneity of this series of compounds, which was previously established in biochemical experiments.
Keywords HEPTHIVTSARCATALYSTReverse transcriptaseNeural network
Identifiers
Full text
Structures
Research group Groupe Weber
Citation
(ISO format)
TRONCHET, Jean M.J. et al. A QSAR study confirming the heterogeneity of the HEPT derivatives series regarding their interaction with HIV reverse transcriptase. In: European Journal of Medicinal Chemistry, 1997, vol. 32, n° 4, p. 279-299. https://archive-ouverte.unige.ch/unige:2798

221 hits

1 download

Update

Deposited on : 2009-09-21

Export document
Format :
Citation style :