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Clinical symptoms and alpha band resting-state functional connectivity imaging in patients with schizophrenia: implications for novel approaches to treatment |
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Published in | Biological Psychiatry. 2011, vol. 70, no. 12, p. 1134-42 | |
Abstract | Schizophrenia (SZ) is associated with functional decoupling between cortical regions, but we do not know whether and where this occurs in low-frequency electromagnetic oscillations. The goal of this study was to use magnetoencephalography (MEG) to identify brain regions that exhibit abnormal resting-state connectivity in the alpha frequency range in patients with schizophrenia and investigate associations between functional connectivity and clinical symptoms in stable outpatient participants. | |
Keywords | Adult — Alpha Rhythm/physiology — Case-Control Studies — Cerebral Cortex/physiology/physiopathology — Cortical Synchronization/physiology — Female — Frontal Lobe/physiology/physiopathology — Humans — Magnetoencephalography — Male — Matched-Pair Analysis — Middle Aged — Neural Pathways/physiology/physiopathology — Parietal Lobe/physiology/physiopathology — Reference Values — Schizophrenia/physiopathology — Schizophrenic Psychology — Severity of Illness Index — Temporal Lobe/physiology/physiopathology | |
Identifiers | PMID: 21861988 | |
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Research group | Neuroréhabilitation assistée par imagerie (910) | |
Project | Swiss National Science Foundation: 320030_129679 | |
Citation (ISO format) | HINKLEY, Leighton B N et al. Clinical symptoms and alpha band resting-state functional connectivity imaging in patients with schizophrenia: implications for novel approaches to treatment. In: Biological psychiatry, 2011, vol. 70, n° 12, p. 1134-42. doi: 10.1016/j.biopsych.2011.06.029 https://archive-ouverte.unige.ch/unige:25364 |