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Scientific article
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Clinical symptoms and alpha band resting-state functional connectivity imaging in patients with schizophrenia: implications for novel approaches to treatment

Published inBiological psychiatry, vol. 70, no. 12, p. 1134-1142
Publication date2011
Abstract

Schizophrenia (SZ) is associated with functional decoupling between cortical regions, but we do not know whether and where this occurs in low-frequency electromagnetic oscillations. The goal of this study was to use magnetoencephalography (MEG) to identify brain regions that exhibit abnormal resting-state connectivity in the alpha frequency range in patients with schizophrenia and investigate associations between functional connectivity and clinical symptoms in stable outpatient participants.

Keywords
  • Adult
  • Alpha Rhythm/physiology
  • Case-Control Studies
  • Cerebral Cortex/physiology/physiopathology
  • Cortical Synchronization/physiology
  • Female
  • Frontal Lobe/physiology/physiopathology
  • Humans
  • Magnetoencephalography
  • Male
  • Matched-Pair Analysis
  • Middle Aged
  • Neural Pathways/physiology/physiopathology
  • Parietal Lobe/physiology/physiopathology
  • Reference Values
  • Schizophrenia/physiopathology
  • Schizophrenic Psychology
  • Severity of Illness Index
  • Temporal Lobe/physiology/physiopathology
Citation (ISO format)
HINKLEY, Leighton B N et al. Clinical symptoms and alpha band resting-state functional connectivity imaging in patients with schizophrenia: implications for novel approaches to treatment. In: Biological psychiatry, 2011, vol. 70, n° 12, p. 1134–1142. doi: 10.1016/j.biopsych.2011.06.029
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Article (Accepted version)
accessLevelPublic
Identifiers
ISSN of the journal0006-3223
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